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Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients — RAMP204  

Non Small Cell Lung Cancer Clinical Trial

Official title:
A Phase 1/2 Study of Avutometinib (VS-6766) in Combination With Adagrasib in Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC) (RAMP 204)

Clinical Trial Summary

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with adagrasib in patients with G12C Non-Small Cell Lung Cancer (NSCLC) who have been exposed to prior G12C inhibitor and experienced progressive disease.

Clinical Trial Description

This is a multicenter, non-randomized, open-label Phase 1/2 study designed to evaluate safety, tolerability and efficacy of avutometinib (VS-6766) in combination with adagrasib in patients with KRAS G12C mutant NSCLC who have been exposed to prior G12C inhibitor and experienced progressive disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05375994
Study type Interventional
Source Verastem, Inc.
Contact Verastem Call Center
Phone 1 781 292 4204
Email clinicaltrials@verastem.com
Status Recruiting
Phase Phase 1/Phase 2
Start date August 1, 2022
Completion date January 1, 2025
View Details
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