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Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER) — BUMPER  

Malignant Melanoma Clinical Trial

Official title:
An Open-label, Uncontrolled, Single Arm Phase II Trial of Buparlisib in Patients With Metastatic Melanoma With Brain Metastases Not Eligible for Surgery or Radiosurgery

Clinical Trial Summary

The study will enrol adult female and male patients with BRAF wild-type melanoma and brain metastases who are not eligible for surgery or radiosurgery and failed prior therapy with ipilimumab, and patients with BRAF V600 mutation-positive melanoma and brain metastases who are not eligible for surgery or radiosurgery and who failed prior therapy with a BRAF inhibitor.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02452294
Study type Interventional
Source University Hospital Tuebingen
Contact Claus Garbe, MD
Phone ++49 7071 29
Email claus.garbe@med.uni-tuebingen.de
Status Recruiting
Phase Phase 2
Start date July 2015
Completion date July 2018
View Details
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