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Multihole Fully Covered Metallic Stents in the Management of Malignant Biliary Obstruction

Malignant Biliary Obstruction Clinical Trial

Official title:
The Use of Multi Holes Fully Covered Metallic Stents Versus Uncovered and Partially Covered Metallic Stents in the Management of Malignant Biliary Obstruction: Randomized Parallel Clinical Trial.

Clinical Trial Summary

multiholes fully covered metallic stents in the management of malignant biliary obstruction

Clinical Trial Description

Malignant biliary obstruction is still a diagnostic and therapeutic challenge requiring a multidisciplinary approach. Most cases are inoperable at the time of diagnosis. Relieving the obstruction and normalizing the serum bilirubin level is usually the first step by biliary catheterization and stent placement. Biliary stent placement has largely replaced surgical bypass for the palliation of malignant biliary obstruction. Rigid plastic stents, despite it is cheap and easily removed, but with limited duration of stent patency. Self-expandable metal stents (SEMS) have larger luminal diameters and provide longer patency time than rigid plastic stents. SEMS are composed of a variety of metals and can be uncovered, partially covered, or fully covered. Uncovered stents are prone to obstruction by tumor growths; however, covered stents may block bile duct branches and are at risk of migration. A multihole self-expandable metallic stent was developed to prevent the obstruction of bile duct branches. In addition, the holes may prevent migration due to small ingrowths which reduce the tension of the membrane ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05786326
Study type Interventional
Source Zagazig University
Contact
Status Recruiting
Phase N/A
Start date March 28, 2023
Completion date June 2024
View Details
See also
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