Impact of Co Enzyme Q10 as Adjuvant Therapy to Letrozole on Spermiogram

Status Completed

Clinical Trial Summary

Worldwide infertility affects about 15 % of reproductive-age couples. In many cases, infertility can't be treated, new treatment options with promising value were involved in the recent clinical trials.

Clinical Trial Description

We will evaluate the impacts of adding coenzyme Q10 to letrozole on spermiogram and sex hormone in men diagnosed with idiopathic oligo/astheno/ teratozoospermia (iOAT) syndrome. The study will include 67 patients which will be randomly separated into two groups, Group (A) 29 patients will be treated with letrozole 2.5mg tablet orally twice a week, Group (B) 38 patient will be treated with a combination of letrozole 2.5 mg tablet orally twice a week plus Co-Q10 400mg per day, both groups complete treatment for three months. Semen sample, serum FSH, estradiol (E2), and testosterone (T) were analyzed at day one, and at the end of one, two, and three months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05847257
Study type	Interventional
Source	Al-Mustansiriyah University
Contact
Status	Completed
Phase	Phase 2
Start date	December 1, 2021
Completion date	October 30, 2022

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