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NCT06103292 Clinical Trial

Calcium Levels in Major Trauma

Major Trauma Clinical Trial

Official title:
Ionized Calcium Level Abnormalities In Major Trauma Patients Pre And Post Receiving Blood Transfusion And Its Relation To Mortality Rate

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06103292
Other study ID # Calcium abnormaities in trauma
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date March 2024
Est. completion date December 2025

Study information
Verified date October 2023
Source Assiut University
Contact HOSSAM ISMAIL, MBBCH
Phone +201090703142
Email hosoabdo1996@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To assess and treat The calcium level abnormalities in major trauma pre and post receiving blood transfusions .

Description:

Primary objective: - to evaluate the level of ionized calcium in multiple trauma patients with massive hemorrhage Secondary objective: - to build a relation between the level of ionized calcium and the degree of hemorrhagic shock

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 150
Est. completion date December 2025
Est. primary completion date September 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: 1. >18 years old - < 70 years 2. Major trauma patients. 3. Admission and Ionized calcium measurement before blood transfusions Exclusion Criteria: 1. patients below 18 years or > 70 years of age. 2. Pregnant women 3. Arrested patients 4. Patients managed outside the hospital and had received blood transfusions

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• ionized calcium levels
measuring calcium level in trauma patients

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Hossam Abdel Rahman Ahmed Ismail

References & Publications (4)

Barry GD. Plasma calcium concentration changes in hemorrhagic shock. Am J Physiol. 1971 Apr;220(4):874-9. doi: 10.1152/ajplegacy.1971.220.4.874. No abstract available. — View Citation

Heckbert SR, Vedder NB, Hoffman W, Winn RK, Hudson LD, Jurkovich GJ, Copass MK, Harlan JM, Rice CL, Maier RV. Outcome after hemorrhagic shock in trauma patients. J Trauma. 1998 Sep;45(3):545-9. doi: 10.1097/00005373-199809000-00022. — View Citation

Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, Pons PT. Epidemiology of trauma deaths: a reassessment. J Trauma. 1995 Feb;38(2):185-93. doi: 10.1097/00005373-199502000-00006. — View Citation

Zink KA, Sambasivan CN, Holcomb JB, Chisholm G, Schreiber MA. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg. 2009 May;197(5):565-70; discussion 570. doi: 10.1016/j.amjsurg.2008.12.014. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary follow up ionized calcium level 24 hrs
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