Hyperfibrinogenemia After Major Trauma

Status Recruiting

Clinical Trial Summary

Assessment of the evolution of fibrinogen plasma level within the first ten days after major trauma in order to determine prevalence of hyperfibrinogenemia (Fg > 4 g/L) and its time to onset.

Clinical Trial Description

In this study, investigators daily investigate fibrinogen plasma levels and fibrinogen antigen in severe trauma patients (Injury severity score > 15) within the first ten days. Investigators then modelize hyperfibrinogenemia profiles according to severity of injuries and physiopathologic mechanisms. Finally, investigators determine predisposing risk factors to develop hyperfibrinogenemia and assess the impact of fibrinogen replacement therapy in initial phase of management of major trauma. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02509390
Study type	Interventional
Source	University Hospital, Montpellier
Contact	Pauline PD DERAS, MD
Phone	+334 67 33 82 56
Email	p-deras@chu-montpellier.fr
Status	Recruiting
Phase	N/A
Start date	September 2014
Completion date	December 2015

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