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Clinical Trial Summary

Major depression is accompanied by cognitive changes as well as alterations in multiple physical functions. The inflammatory system is altered generally toward a pro-inflammatory state. Antidepressants are associated with a decrease in this proinflammatory state. This study aims to generate pilot data concerning a possible link between cognition, inflammation and response to treatment. The cognitive function of subjects with major depression will be tested before and after treatment with duloxetine. Inflammatory markers will be measured at both time points.


Clinical Trial Description

n/a


Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science


Related Conditions & MeSH terms


NCT number NCT01391221
Study type Interventional
Source Centre de recherche Fernand-Seguin, Hôpital Louis-H. Lafontaine
Contact Louise Normandeau, Nursing
Phone 514-251-4000
Email urb.crfs@ssss.gouv.qc.ca
Status Recruiting
Phase Phase 4
Start date July 2011
Completion date August 2013

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