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Machine Learning clinical trials

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NCT ID: NCT06428344 Not yet recruiting - Dental Caries Clinical Trials

Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study

Start date: June 1, 2024
Phase:
Study type: Observational

This clinical trial was designed as a prospective, multicenter, multi-reader multi-case (MRMC), superiority, parallel-controlled study. Participants who met the trial criteria and signed the informed consent form were enrolled. The trial group involved diagnoses of caries on panoramic radiographs using an artificial intelligence-assisted diagnostic system, while the control group involved diagnoses made by dental practitioners specializing in operative dentistry and endodontics with five years of experience, who interpreted oral panoramic radiographs to determine the presence and severity of caries.

NCT ID: NCT06423066 Not yet recruiting - Lung Cancer Clinical Trials

Developing a Machine Learning Model to Predict Pleural Adhesion Preoperatively Using Pleural Ultrasound

Start date: June 1, 2024
Phase:
Study type: Observational

This study aims to investigate the accuracy of using pleural ultrasound (USP) to identify pleural adhesions in patients who plan to receive video-assisted thoracoscopic surgery. It employs three-dimensional convolutional neural network (3D-CNN) technology to process USP-related images and video data for machine learning, and to establish a diagnostic model for identifying pleural adhesions using 3D-CNN-USP. The study will determine the sensitivity, specificity, positive predictive value, and negative predictive value of 3D-CNN-USP in identifying pleural adhesions. Additionally, it will explore the feasibility and effectiveness of using 3D-CNN-USP for preoperative identification of pleural adhesions in VATS, thereby supporting the implementation of day surgery in thoracic surgery and ultimately serving clinical practice.

NCT ID: NCT06421480 Not yet recruiting - Machine Learning Clinical Trials

Using Machine Learning to Detect Risky Behavior in Psychiatric Clinics

Start date: June 20, 2024
Phase:
Study type: Observational

The aim of this study is to ensure the safety of patients in a psychiatric clinic and to detect risky behaviors by using machine learning method. Risky behaviors are defined as behaviors that are personally, socially and developmentally undesirable and endanger life and health.Patient safety and maintaining a safe environment are among the primary duties of healthcare professionals. Suicide is the most important evidence-based risk factor, especially among individuals with psychiatric illnesses, and is one of the most important factors that threaten patient safety. At the end of this study, it is aimed to detect risky behaviors of patients before they harm themselves and to enable healthcare professionals to make early intervention for these behaviors, thus supporting a safe treatment environment, with the computer system that has been trained with the machine learning model installed in the clinics.

NCT ID: NCT06290739 Recruiting - Clinical trials for Intrahepatic Cholangiocarcinoma

A Machine-learning Model to Predict Lymph Node Metastasis of Intrahepatic Cholangiocarcinoma

Start date: February 7, 2024
Phase:
Study type: Observational

The object of this study is to develop a model for prediction of lymph node metastasis among intrahepatic cholangiocarcinoma (ICC) patients. Intrahepatic cholangiocarcinoma is the second most common kind of primary liver cancer, accounting for approximately 10%-15%. There is a lack of agreement regarding the necessity of performing lymph node dissection (LND) in patients with ICC. Currently, the percentage of LND is below 50%, and the rate of sufficient LND (≥6) has plummeted to less than 20%. Consequently, a large proportion of patients are unable to acquire LN status, which hinders the following systematic treatment strategies after surgery:. Therefore, our objective is to construct a LN metastasis model utilizing machine learning techniques, including patients' clinical data and pathology information, with the goal of offering a reference for patients who have not undergone LND or have had inadequate LND.

NCT ID: NCT06278272 Completed - Clinical trials for Chronic Pancreatitis

AI Evaluation of Pancreatic Exocrine Insufficiency in CP Patients

Start date: March 1, 2023
Phase:
Study type: Observational

Early assessment of pancreatic exocrine insufficiency (PEI) is crucial for determining appropriate chronic pancreatitis (CP) treatment plans, thereby avoiding unnecessary suffering and further complications in patients. A total of 504 patients with CP who underwent fecal elastase-1 test and contrast-enhanced CT at Changhai Hospital between January 2018 and April 2023 were enrolled in this study. The investigators aim to establish a fully automated workflow to establish a PEI classification model based on radiomic features, semantic features and deep learning features on enhanced CT images for evaluating the severity of PEI.

NCT ID: NCT06277297 Recruiting - Clinical trials for Magnetic Resonance Imaging

Prognotic Role of CMR in Takotsubo Syndrome

EVOLUTION
Start date: November 9, 2022
Phase:
Study type: Observational

The primary objective of this observational registry is to develop a comprehensive clinical and imaging score (incorporating echocardiography and cardiac magnetic resonance data) that enhances risk stratification for patients with Takotsubo syndrome. The secondary objectives of this registry are as follows: Investigate the diagnostic value of cardiac magnetic resonance parameters in predicting in-hospital and long-term outcomes in patients with Takotsubo syndrome. Compare the proposed risk stratification score for patients with Takotsubo syndrome with previously existing scores. Investigate the contribution of machine learning models in predicting in-hospital and long-term outcomes compared to standard clinical scores. The design and rationale of this registry are available at 10.1097/RTI.0000000000000709

NCT ID: NCT06208046 Completed - Gastric Cancer Clinical Trials

Predict 5-Year Survival in Elderly Gastric Cancer

Start date: July 1, 2023
Phase:
Study type: Observational

In this study, elderly patients with gastric cancer who underwent radical gastrectomy in Union Hospital Affiliated to Fujian Medical University from 2012 to 2018 were included as a derived cohort, and the training set and internal validation set were randomly divided by 4:1. Machine learning strategies of random forest, decision tree and support vector machine are used to construct survival prediction model. Each model was tested in an internal validation set and an external validation set consisting of patients from two other large medical centers.

NCT ID: NCT06204133 Recruiting - Clinical trials for Artificial Intelligence

Model Study on Cervical Cancer Screening Strategies and Risk Prediction

Start date: November 1, 2023
Phase:
Study type: Observational

By collecting non-image medical data of women undergoing cervical screening in multiple centers in China, including age, HPV infection status, HPV infection type, TCT results, and colposcopy biopsy pathology results, a multi-source heterogeneous cervical lesion collaborative research big data platform was established. Based on artificial intelligence (AI) machine learning, cervical lesion screening features are refined, a multi-modal cervical cancer intelligent screening prediction and risk triage model is constructed, and its clinical application value is preliminarily explored.

NCT ID: NCT06163781 Recruiting - Clinical trials for Artificial Intelligence

Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning

ABC
Start date: February 19, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency department with a clinical indication for a blood culture analysis (according to the treating physician). The primary endpoint is 30-day mortality. Key secondary outcomes are: - hospital admission rates - in-hospital mortality - hospital length-of-stay. In the intervention group, the physician will follow the advice of our blood culture prediction tool. In the comparison group all patients will undergo a blood culture analysis.

NCT ID: NCT06120478 Completed - Machine Learning Clinical Trials

Prediction of Risk Factors for Adverse Events After Head and Neck Vascular Recanalization Surgery Based on Machine Learning Models

Start date: January 1, 2019
Phase:
Study type: Observational

Prediction of risk factors for adverse events after head and neck vascular recanalization surgery based on machine learning models