Molecular Screening for Lynch Syndrome in Southern Denmark

Status Completed

Clinical Trial Summary

A clinically applicably strategy for molecular screening for Lynch Syndrome has been implemented in the Region of Southern Denmark.

Based on sequential analysis with immunohistochemistry and methylation analysis, patients with possible hereditary colorectal cancer are identified. These patients are offered genetic risk assessment and counselling.

The study hypothesis is that molecular screening will identify more patients with Lynch Syndrome than the family history alone.

Prospective data collection is performed using established clinical databases.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Colorectal Cancer
Colorectal Neoplasms, Hereditary Nonpolyposis
HNPCC
Lynch Syndrome
Syndrome

Clinical Trial Details

NCT number	NCT01216930
Study type	Observational
Source	Vejle Hospital
Contact
Status	Completed
Phase	N/A
Start date	October 2010
Completion date	September 2015

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