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Lymphoma clinical trials

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NCT ID: NCT01139359 Withdrawn - Lymphoma Clinical Trials

Safety Study of Darinaparsin in Combination With Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) to Treat Lymphoma

Start date: June 2010
Phase: Phase 1
Study type: Interventional

This study is a Phase I trial of Darinaparsin in combination with CHOP for the treatment of lymphoma. Eligible patients will not have had any previous anti-cancer treatment and will be eligible to receive CHOP alone.

NCT ID: NCT01138579 Withdrawn - Leukemia Clinical Trials

Study of the Trifunctional Antibody FBTA05 and Donor Lymphocyte Infusion in B-cell Lymphoma After Allogeneic Stem Cell Transplantation

STP-LYM-01
Start date: August 2010
Phase: Phase 1/Phase 2
Study type: Interventional

This study is an investigator driven, open-label, non-randomized, uncontrolled, dose escalating Phase I/II study evaluating the safety and preliminary efficacy of the trifunctional bispecific antibody FBTA05 in combination with donor lymphocyte infusions (DLI) for treatment of relapsed or refractory disease in CD20 positive either low- or high-grade non-Hodgkin´s lymphoma after allogeneic transplantation

NCT ID: NCT01101581 Withdrawn - Clinical trials for Diffuse Large B-cell Lymphoma

Study of Veltuzumab and 90Y-Epratuzumab in Relapsed/Refractory, Aggressive NHL

Start date: May 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this study is to evaluate a new approach to immunotherapy in NHL by combining two antibodies, veltuzumab and epratuzumab. For treatment, epratuzumab has also been attached to a radioactive isotope called 90yttrium (90Y-epratuzumab). Veltuzumab and 90Y-epratuzumab attack different areas on lymphoma cells. Because of this, treatment with the combination may provide more effective treatment in NHL than either veltuzumab or 90Y-epratuzumab given alone.

NCT ID: NCT01101412 Withdrawn - Lymphoma Clinical Trials

Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

RATIONALE: Antimicrobial solution comprising trimethoprim-sulfamethoxazole, edetate calcium disodium, and ethanol may help prevent blockages and infections from forming in patients with central venous access catheters or peripheral venous catheters. PURPOSE: This randomized trial is studying an antimicrobial solution or saline solution in maintaining catheter patency and preventing catheter-related blood infections in patients with malignancies.

NCT ID: NCT01044004 Withdrawn - Fatigue Clinical Trials

Evaluate the Efficacy of Armodafinil for Patients With B-cell Lymphoma and Severe Fatigue

Start date: March 2010
Phase: N/A
Study type: Interventional

To determine whether armodafinil is more effective than placebo in reducing fatigue.

NCT ID: NCT00983944 Withdrawn - Lymphoma Clinical Trials

Rituximab and Combination Chemotherapy With or Without Bleomycin Sulfate in Treating Patients With Primary Mediastinal Large B-Cell Lymphoma

Start date: September 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving rituximab together with combination chemotherapy may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective when given with rituximab in treating large B-cell lymphoma. PURPOSE: This randomized phase II trial is studying how well rituximab and combination chemotherapy work when given with or without bleomycin sulfate in treating patients with primary mediastinal large B-cell lymphoma.

NCT ID: NCT00972101 Withdrawn - Lymphoma Clinical Trials

Infusion of Expanded Cord Blood T Cells

Start date: September 2009
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to learn if treating umbilical cord blood with growth factors before a transplant can help to improve the body's ability to accept the cord blood transplants.

NCT ID: NCT00969085 Withdrawn - Clinical trials for Cutaneous T-cell Lymphoma

Trial of Curcumin in Cutaneous T-cell Lymphoma Patients

Start date: November 2012
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to learn if treatment with curcumin can help to decrease the size of lesions and/or decrease itching in patients with MF or SS. The safety of curcumin will also be studied.

NCT ID: NCT00939172 Withdrawn - Lymphoma Clinical Trials

TTP607 in Refractory Solid Malignancies

Start date: March 2010
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable dose of TTP607 that can be given to patients with a solid tumor or lymphoma. The safety of TTP607 will also be studied. Researchers will also do pharmacokinetic (PK) testing of TTP607. PK testing measures the amount of a drug in the body at different time points.

NCT ID: NCT00900120 Withdrawn - Lymphoma Clinical Trials

Collecting and Storing Blood Samples From Patients With Cancer

Start date: March 2004
Phase:
Study type: Observational

RATIONALE: Collecting and storing samples of blood from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing blood samples from patients with cancer.