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Lymphedema of Upper Arm clinical trials

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NCT ID: NCT06144164 Recruiting - Breast Cancer Clinical Trials

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

Start date: November 16, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.

NCT ID: NCT05203835 Recruiting - Clinical trials for Lymphedema of Upper Arm

Trial of Acebilustat for the Treatment of Upper Arm Lymphedema

HEAL
Start date: July 27, 2022
Phase: Phase 2
Study type: Interventional

This study is designed to investigate the response of unilateral upper extremity (arm) lymphedema, during pharmacologic treatment of lymphedema with oral placebo and oral acebilustat. Participants will receive "study drug" (Acebilustat or placebo), for 9 months. For 3 of these months, the participant will receive placebo; for 6 of these months, the participant will receive active ingredient, acebilustat. The study is blinded which means that the participant will not be told which study pill they are taking.

NCT ID: NCT05142800 Recruiting - Breast Cancer Clinical Trials

Screening For BCRL In Targeted Therapy For Breast Cancer

Start date: December 13, 2018
Phase:
Study type: Observational

This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer. A Perometer and Sozo devise will be used to measure volume changes

NCT ID: NCT04934098 Recruiting - Breast Neoplasms Clinical Trials

Adjustable Compression Wrap Versus Compression Bandage Reduce to Breast Cancer-related Lymphedema

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This is a randomized clinical trial with women with lymphedema secondary to breast cancer. The intervention will consist of the use of self-adjusting clothing versus compressive bandaging (routine treatment of the institution). Self-adjusting clothing is expected to be more effective for the treatment of lymphedema reduction, when compared to standard treatment, in addition to promoting a better quality of life and functionality.

NCT ID: NCT04908254 Recruiting - Lymphedema Clinical Trials

A Multi-center Randomized Control Cross-over Study to Evaluate the Safety and Effectiveness of the Dayspring Active Wearable Compression Device vs. an Advanced Pneumatic Compression Device for Treating Breast Cancer Related Lymphedema

NILE
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

To evaluate the Dayspring Active Wearable Compression Device in contrast to an advanced pneumatic compression device (APCD)

NCT ID: NCT04821609 Recruiting - Breast Cancer Clinical Trials

Supervised Resistance TRaining amONG Women at Risk of Breast Cancer Related Lymphedema

STRONG-B
Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Breast cancer (BC) is the most common neoplasm in Chile, and its medical treatment leads to high survival. One-third of survivors will develop BC-related lymphedema. Lymphedema is a chronic condition characterized by increased volume in the ipsilateral arm to surgery. A higher volume is associated with decreased physical functionality and quality of life. Recent studies suggest that resistance training could control arm volume through increased muscle mass development, improving physical functionality and quality of life for patients. To our knowledge, there is no study that has analyzed the effect of a resistance training program among women at risk of BC-related lymphedema on arm volume and quality of life. The purpose of this study is to determine the effect of resistance training on the arm volume and quality of life among women with adjuvant chemotherapy and high risk of BC-related lymphedema compared to a control group with regular physical therapy management, which does not include resistance training. This is a randomized controlled study. It will be held at the Complejo Asistencial Dr. Sotero del Río, which receives all patients from the South East Metropolitan Health Service. Participants: 106 women receiving adjuvant chemotherapy for BC who have undergone axillary lymph node dissection or with obesity will be recruited. The difference in volume between the arms will be evaluated with optoelectric equipment. Quality of life with The European Organization for Research and Treatment in Cancer Quality of Life C-30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Breast Cancer-Specific Quality of Life Questionnaire BR23 (EORTC QLQ-BR23) questionnaires, both validated in Chile; the handgrip with a dynamometer; and physical functionality with the six-minute walk test. Volunteers will be randomly assigned to the resistance training group or control group. The resistance training group will consist of twice a week supervised sessions, for 12 weeks. The exercises will be for arms and legs, self-loading type, and with external weights. The control group will follow the usual physical therapy management, which does not include resistance training. Subsequently, volunteers will be evaluated at the third and sixth months after completion of the 12 weeks resistance training program.

NCT ID: NCT04690439 Recruiting - Breast Cancer Clinical Trials

Photobiomodulation Therapy for the Management of Breast Cancer-related Lymphedema

LymphLight
Start date: February 22, 2021
Phase: N/A
Study type: Interventional

Up to one out of five patients with breast cancer will develop lymphedema in the upper extremity after cancer treatment. Patients with breast cancer-related lymphedema (BCRL) suffer from pain, heaviness, tightness, and a decreased range of motion. Photobiomodulation therapy (PBMT) is a non-invasive therapy based on the application of visible and/or near-infrared light produced by a laser diode or a light-emitting diode. The scientifically proven biologic effects of PBM are improved wound healing, and a reduction in pain, inflammation, and oedema. Therefore, the aim of this study is to evaluate the effectiveness of PBMT on the management of BCRL.

NCT ID: NCT04296929 Recruiting - Breast Cancer Clinical Trials

The Effect of Complex Decongestive Physiotherapy on Sensory Parameters in Breast Cancer Related Lymphedema.

Start date: November 28, 2019
Phase: N/A
Study type: Interventional

The aim of this study was to determine the effect of complex decongestive physiotherapy in women with unilateral breast cancer-related lymphedema on sensory parameters.

NCT ID: NCT04203069 Recruiting - Clinical trials for Lymphedema of Upper Arm

Auto-Adjustable MOBIDERM® Autofit NIGHT-time Compression Armsleeve in the Upper Limb LYMphedema in Maintenance Phase

LYMphoNIGHT
Start date: July 1, 2020
Phase: N/A
Study type: Interventional

This study aims to assess Auto-Adjustable MOBIDERM® Autofit Armsleeve effect on upper limb volume excess after 3 months of maintenance phase treatment in patients with secondary upper limb lymphedema following breast cancer. Half of the patient will wear a day-time and night time compression garment (MOBIDERM Autofit) for 3 months during the maintenance phase, while the other half will only wear day-time compression garment.

NCT ID: NCT04138667 Recruiting - Clinical trials for Lymphedema of Upper Arm

Responsiveness of Outcome Scales in Breast Cancer Related Lymphedema

Start date: October 19, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate and compare responsiveness of current lymphedema assessment scales validated in Turkish.