Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery

Status Recruiting

Clinical Trial Summary

During cardiac surgery with cardiopulmonary bypass , pulmonary dysfunction remains to be a problem complicating the postoperative course of the patients.Remote ischemic preconditioning(RIPC) with transient upper limb ischemia/reperfusion is a novel, simple, cost-free,non-pharmacological and non-invasive strategy.Recent several trials suggested that RIPC could provide pulmonary protection by reducing serum biomarkers,however,whether the RIPC can improve the clinical outcomes in patients undergoing on-pump cardiac surgery,is still uncertain.

The study hypothesis is: remote ischemic preconditioning will provide lung-protective effect and improve clinical outcomes in patients undergoing cardic surgery.

Clinical Trial Description

Remote ischemic preconditioning (RIPC) protocol will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood pressure cuff inflated to a pressure 200mmHg ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03016182
Study type	Interventional
Source	Xuzhou Medical University
Contact	Liu Su, M.D/Ph.D
Phone	+86-18118309692
Email	xyfymzk@163.com
Status	Recruiting
Phase	N/A
Start date	February 7, 2017
Completion date	February 2018

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