Lung Injury Clinical Trial
Official title:
Acute Lung Injury After Aortic Valve Surgery
The purpose of this prospective, randomized clinical trial is to understand and measure lung
injuries caused by CPB in aortic valve surgery.
Study questions:
- Is there any correlation between the release of pro-inflammatory biomarkers and lung
injury degree?
- Is there any correlation between oxyhaemodynamic parameters and lung injury degree?
- Is there any correlation between oxyhaemodynamic parameters and the release of
pro-inflammatory biomarkers?
- Are budesonide, erdostein and acetylcystein effective in the prevention of lung
injuries?
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - elective aortic valve surgery patient - written consent Exclusion Criteria: |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Finland | Oulu University hospital | Oulu |
Lead Sponsor | Collaborator |
---|---|
University of Oulu |
Finland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | lung injury | within the first 3 days after surgery | No |
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