Cognitive Function Clinical Trial
Official title:
Reducing Commuter Air Pollutant Exposure by Cabin Air Filtration
Traffic related air pollution is a well-recognised and much studied contributor to smog and
is linked to a number of adverse health outcomes. Although traffic pollutants can travel
long distances, exposure to the highest levels of the raw emissions can occur closest to the
source; e.g. in a car in dense traffic conditions. Time spent in-vehicle may contribute up
to half of commuters' daily exposure to certain air pollutants. Most new cars now have or
allow for a cabin air filter, but it is not known how well cabin air filtration can reduce
exposure to traffic-related air pollution.
This intervention study will measure commuters' exposure to air pollutants in rush hour
traffic. It will evaluate the impact of this exposure on stress hormones in saliva, and
short term cardiopulmonary health indicators such as blood pressure, heart rate variability
and respiratory inflammation. It will also look at effects on cognition (mental processing
and judgement) in this real world environment where any deficit could be important to
safety. In addition, the study will examine whether cabin air filtration can reduce the
exposure to traffic related air pollutants and result in improvements in short term
cardiopulmonary and cognitive function. This research will contribute to our understanding
of how this environment contributes to Canadians' overall air pollution exposure as well as
the potential health impacts. It will also test a potentially valuable and economical means
of reducing exposure to traffic related air pollution in a commuting environment. The study
may also guide the future implementation of the use of cabin filters as an exposure
reduction intervention.
Overall Project Objectives:
Can cabin air filtration effectively reduce exposure to traffic related air pollution? Does
commuter exposure to air pollution affect short term stress, and cardiopulmonary and
cognitive function? Can cabin air filtration mitigate the health effects of commuters'
exposure to air pollution?
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention
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