TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection

Lung Diseases Clinical Trial

Official title:

Comparison Between Thoracic Epidural Anaesthesia, Erector Spinae Block and Paravertebral Block During Single-lung Ventilation for Lung Resection in Lateral Decubitus Position: A Prospective Randomized Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05211791
• Other study ID #: TEA in single lung ventilation
• Status: Recruiting
• Phase: N/A
• Start date: January 10, 2022
• Est. completion date: October 20, 2023

Study information

• Verified date: May 2023
• Source: South Egypt Cancer Institute
• Contact: Alaa A Elzohry, MD
• Phone: +201007356462
• Email: alaa.zohiry[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Thoracotomy operations are known to be painful surgical procedures, so providing effective intraoperative and postoperative analgesia is so important for all anaesthesiologists. Ineffective pain management interferes with deep breathing, coughing, and remobilization resulting in atelectasis and pneumonia.

Ultrasound-guided ESP block is a myofascial plane block that provides analgesia for thoracic or abdominal segmental innervation depending on the level of the injection site. Thoracic epidural analgesia (TEA) is considered the gold standard analgesic technique for thoracic surgeries. But the invasiveness of this technique, the rare but serious neurologic complications and the failure rates up to 30% are the disadvantages of epidural analgesia

Description:

The aim of this study is to compare the effect of different blocks as TEA, erector spinae block or paravertebral block on improving peri-operative analgesia and post-operative outcome in pulmonary resection in adult patients.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: October 20, 2023
• Est. primary completion date: June 10, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• aged between 18 to 70 years old for elective lung resection. with American Society of Anesthesiology physical status (ASA-PS) I-III

Exclusion Criteria:

• Total pneumonectomy

• Hepatic or renal dysfunction.

• contraindications for epidural anesthesia as Coagulopathy and neurological and spinal deficits.

• emergency cases

Related Conditions & MeSH terms

• Acute Pain
• Lung Diseases
• Pain, Acute

Intervention

Procedure:
• erector spinae block
Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia
• paravertebral block anesthesia
Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia
• Thoracic epidural anesthesia
insertion of Thoracic epidural catheter for anesthesia analgesia at level of T6

Locations

Country	Name	City	State
Egypt	South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
South Egypt Cancer Institute

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	peri-operative analgesia	Visual Analogue score (resting and during cough) from 0 (no pain) to 10 (worst pain pain measurement	up to 48 hours postoperative