Clinical Trials Logo
  1. Home
  2. Lung Diseases, Obstructive
  3. NCT02439333

Prospective Randomized Study of Nasal High Flow in Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Lung Diseases, Obstructive Clinical Trial

Clinical Trial Summary

The main oxygen therapy to the patients with acute exacerbation of Chronic obstructive pulmonary disease, who are mild to moderate respiratory insufficiency (arterial blood gas analysis showed pH = 7.35, PO2 < 60mmHg,PaCO2＞45mmHg) or have achieved the traditional noninvasive ventilation support standard but can not tolerate or reject, was nasal catheter, venturi mask and other conventional oxygen therapy. All these inaccurate inhaled oxygen concentration methods with inadequate heating and humidifying lead to poor patient tolerance and adverse reactions such as airway secretions discharge disorders. The high flow nasal respiratory therapy (Nasal high flow, NHF) utilises higher gas flow rates than conventional low-flow oxygen systems. The devices used deliver heated and humidified oxygen at a flow of up to 60 litres per minute via nasal cannulas with low level continous positive airway pressure. This study is a prospective randomized study. AECOPD patients with no severe respiratory failure are treated with NHF and conventional oxygen therapy respectively. The target is that NHF can increase the comfort degree of patients,reduce the rate of endotracheal intubation, and shorten the time of hospitalization.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02439333
Study type Interventional
Source Beijing Chao Yang Hospital
Contact
Status Completed
Phase N/A
Start date July 2015
Completion date July 15, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT01860898 - A Phase I Study of iPS Cell Generation From Patients With COPD N/A
Completed NCT00281216 - Innate and Adaptive Immunity in Individuals Experiencing Chronic Obstructive Pulmonary Disease Exacerbations N/A
Completed NCT00281190 - Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function N/A
Completed NCT00159341 - Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD) Phase 1
Completed NCT00281242 - Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease N/A
Completed NCT00281203 - Comparison of Alveolar Macrophages in Healthy Individuals Versus Individuals With COPD N/A
Completed NCT00281229 - T Lymphocyte Cells in Individuals Experiencing an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Completed NCT00069823 - Study of Acid Reflux in Asthma Phase 3
Completed NCT00006513 - Assessing the Occupation Burden in COPD N/A
Completed NCT00000621 - Feasibility of Retinoic Acid Treatment in Emphysema (FORTE) Phase 2
Completed NCT00006306 - Effects of Chronic Ozone Exposure on Lung Function N/A
Completed NCT00000569 - Lung Health Study II Phase 3
Completed NCT00005425 - Statistical Analysis of Vlagtwedde-Vlaardingen Data Set N/A
Completed NCT00005720 - Lay-Led Smoking Cessation Approach for Southeast Asian Men N/A
Completed NCT00000568 - Lung Health Study (LHS) I and III Phase 3
Completed NCT00005281 - Early Risk Predictors For Chronic Pulmonary Disease N/A
Not yet recruiting NCT05286918 - Antibiotic Stewardship in AECOPD Through CRP-Guided Management N/A
Recruiting NCT05565872 - Effects of Supervision During a Community-based Exercise Intervention (Urban Training) in Patients With COPD N/A
Not yet recruiting NCT02928666 - Integration of Guidelines for Comorbidities N/A
Completed NCT02306473 - The Leaky Lung Test Early Phase 1