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Clinical Trial Summary

This is a clinical trial designed to test the hypothesis that measuring the absorption and excretion of inhaled mannitol will provide a clinically useful marker of airway epithelial permeability in asthma.


Clinical Trial Description

A cohort of subjects with asthma and healthy controls will be exposed to inhaled mannitol according to FDA approved protocols for bronchoprovocation. Mannitol will be measured in the bloodstream and urine and used to determine an airway permeability index. This is a proof of concept study and not a trial of new therapeutics. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02306473
Study type Interventional
Source University of Rochester
Contact
Status Completed
Phase Early Phase 1
Start date October 2015
Completion date December 1, 2017

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