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Lung Diseases, Obstructive clinical trials

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NCT ID: NCT04903639 Completed - OSA Clinical Trials

Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases

Start date: August 1, 2018
Phase:
Study type: Observational [Patient Registry]

The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as Overlap Syndrome (OS). The coexistence of these diseases have cardiovascular morbidity and mortality. The aim of this study is to assess the prevalence of OSA in COPD patients. 100 COPD patients (obese and non-obese) performed sleep questionnaires and polysomnogram.

NCT ID: NCT04895124 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Second Follow-up Study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers

Ribo III
Start date: May 25, 2021
Phase:
Study type: Observational

Between 2012 and 2014, a cohort of 90 COPD subjects of disease severity grades GOLD I-IV as well as 60 healthy control subjects (30 smokers and 30 non-smokers) have been examined regarding different clinical and blood/ sputum derived biomarkers at the investigators' research center. Of this cohort, 116 subjects were re-invited for the first follow-up study Ribolution II (NTC02522026) after 3 years (+/- 6 months) and data on the clinical course and treatment changes was obtained. This second follow-up study will re-examine all available subjects regarding disease course and treatment changes after 3 years (+/-6 months) for the investigation of ncRNA/ transcriptome biomarkers for their potential to indicate disease progression. In addition, biobanking of respective biosamples for potential future COPD biomarker research will be conducted.

NCT ID: NCT04890080 Completed - COPD Clinical Trials

Resting Heart Rate in Chronic Obstructive Pulmonary Disease

Start date: January 2017
Phase: N/A
Study type: Interventional

110 COPD patients who were participated in the PR program were included in the study. Resting Heart Rate , pulmonary functions, functional capacity, perception of dyspnea, quality of life and psychological symptoms compared before and after PR.

NCT ID: NCT04880486 Completed - Quality of Life Clinical Trials

Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Start date: September 18, 2019
Phase: N/A
Study type: Interventional

Using weight training with virtual reality can help after discharge patients of acute exacerbation of chronic obstructive pulmonary disease, which maintained their quality of life, and improved their exercise capacity, pulmonary function, readmission condition.

NCT ID: NCT04877353 Completed - Clinical trials for Acute Respiratory Failure Post Surgical (Diagnosis)

Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.

NCT ID: NCT04876677 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Functional Respiratory Imaging Study

DARWiIN
Start date: May 25, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the stepping-up effect from a double ICS/LABA DPI therapy to a triple DPI therapy on airway geometry and lung ventilation

NCT ID: NCT04873856 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Multidimensional Individualized Nutritional Therapy for Individuals With Severe COPD

MINDNUT
Start date: May 21, 2021
Phase: N/A
Study type: Interventional

Individuals with severe chronic pulmonary disease often life isolated with a high burden of symptoms. Nutritional risk and low quality of life are common, and both associated with increased societal cost and poor prognosis. COPD is a complex and progressive disease with changing clinical states that influences nutritional status and quality of life in different ways. The primary aim is to improve quality of life for individuals with severe COPD. 120 individuals are recruited from the outpatient clinic at Nordsjællands Hospital in Denmark to a randomized controlled trial with two parallel groups (intervention and control). The intervention will last for 3 months comprising four elements including nutritional plan, regular contact, informal caregiver/friendly reminder and a weight dairy. We expect that the intervention will improve quality of life, nutritional status and prognosis.

NCT ID: NCT04842903 Completed - Anxiety Clinical Trials

Effect of Therapeutic Touch on Sleep Quality and Anxiety in Individuals With Chronic Obstructive Pulmonary Disease

Start date: March 15, 2018
Phase: N/A
Study type: Interventional

Purpose: The purpose is to determine the effect of therapeutic touch on the sleep quality and anxiety of individuals with chronic obstructive pulmonary disease. Material and methods: This study was conducted between March 2018 and March 2019 as a randomized controlled experimental study conducted with pre-test post-test model. In addition to the routine nursing care, therapeutic touch (TT) and study scales were applied to the experimental group for a total of three sessions, once a day and 10 minutes each, for three consecutive days and only study scales were applied to the control group. The data was collected using Personal Information Form, Richard-Campbell Sleep Questionnaire and State Anxiety Inventory.

NCT ID: NCT04840628 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

The Relationship Between the Neural Drive and Intrinsic Positive End-expiratory Pressure

Start date: November 20, 2020
Phase: N/A
Study type: Interventional

To investigate the relation the nreural drive and intrinsic positive end-expiratory pressure(PEEPi) of the chronic obstructive pulmonary disease(COPD) patients with respiratory failure.In present study the PEEPi of COPD patients was increased by increasing the resistance of the respiratory system, the change of the neural drive was recorded.

NCT ID: NCT04834037 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV). Objective: Aim of the study is to determine the effect of provision of information and supportive nursing care on blood gas, vital signs, anxiety, stress and agitation levels in COPD patients treated with NIV. Research Methodology: A randomised controlled design was used between September-December 2019. The universe of the study consisted of COPD patients treated with NIV in intensive care unit in a state hospital. A total of 60 patients, composed of 30 interventions and 30 controls, were randomly included in the sample. Provision of information and supportive nursing care was applied to the patients in the intervention group. The data were evaluated with SPSS program. Results: Following the intervention, the findings showed that the provision of information and supportive nursing care has a positive effect on the blood gas, vital signs, anxiety, stress and agitation levels of patients. Conclusions: The provision of information and supportive nursing care is recommended to alleviate anxiety, stress and agitation in COPD patients treated with NIV