Lung Cancer Clinical Trial
— DECANPHAROfficial title:
Adherence to Lung Cancer Screening by Low-dose Thoracic CT in Haut-Rhin Department, France.
The main objective of the study is to measure adherence to a lung cancer screening program using low-dose thoracic CT.
Status | Recruiting |
Enrollment | 126 |
Est. completion date | November 2026 |
Est. primary completion date | November 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 50 Years to 74 Years |
Eligibility | Inclusion Criteria: - Patients aged 50 to 74 years - Smoking OR having smoked (withdrawal of <15 years): =15 cigarettes/day for =25 years OR =10 cigarettes/day for =30 years - Affiliated or beneficiary of a social security scheme - Written informed consent Exclusion Criteria: - Inability to walk up two flights of stairs without stopping - BMI > 35 kg/m² - Recent chest CT scan < 1 year - Personal history of lung cancer < 5 years or under treatment - Personal history of cancer being monitored by chest CT scan - Contraindication to lung cancer treatment or diagnostic investigations - Current or recent respiratory symptoms immediately suggestive of lung cancer - Pregnant or breast-feeding woman - Person under court protection, guardianship or curatorship - Person deprived of liberty by judicial or administrative decision. |
Country | Name | City | State |
---|---|---|---|
France | Cabinet de médecine générale | Colmar | Haut-Rhin |
Lead Sponsor | Collaborator |
---|---|
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Rate of included patients having undergone the first screening scan | T0 | ||
Secondary | Rate of patients who refused to participate in the screening program | 1 year | ||
Secondary | Rate of included patients having completed CT scans at each stage of follow-up | 3 years | ||
Secondary | Number of patients newly committed to smoking cessation during the screening period | 3 years | ||
Secondary | Tobacco consumption | 3 years | ||
Secondary | Radiation doses received at each CT scan | 3 years | ||
Secondary | Organizational constraints of the screening program | Organizational constraints of the screening program will be assessed on a subgroup of general practitioners by semi-structured interviews | before starting the study | |
Secondary | Stage at diagnosis (TNM classification) of patients with lung cancer | The stages at diagnosis of patients with lung cancer included in the study will be compared with those of undetected patients (data from the Haut-Rhin Cancer Registry). | 3 years |
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