Lung Cancer Clinical Trial
Official title:
Evaluation of the the Effectiveness of the Autologous Blood Patch Method in Transthoracic Lung Biopsies Using the Coaxial Technique
Verified date | June 2023 |
Source | Trakya University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
In this retrospective study, investigators aimed to evaluate the effectiveness of the autologous blood patch method in percutaneous transthoracic lung biopsies performed with the coaxial technique.
Status | Completed |
Enrollment | 240 |
Est. completion date | February 20, 2021 |
Est. primary completion date | November 20, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patients older than 18 years - Patients who underwent percutaneous transthoracic tru cut biopsy - Patients undergoing interventional procedures by radiologists with equal experience - Patients who were able to obtain sufficient samples with the applied biopsy (technical success of percutaneous transthoracic biopsy) - Patients whose medical records are fully accessible and whose data are reliable Exclusion Criteria: - Patients whose laboratory bleeding parameters are not suitable for the procedure (platelets<100000/mm3, INR>1.5) - Pregnancy - Patients with increased risk of pneumothorax due to other etiologies (bulla, blep, chronic obstructive pulmonary disease, cystic fibrosis) - Patients receiving anticoagulant antiplatelet therapy - Patients with persistent cough - Patients with a history of recent lung travma, pneumothorax, hemoptysis or pulmonary hemorrhage - Patients with severe psychiatric diseases such as psychosis or dementia that limit cooperation with the patient - Patients with anatomic deformity (advanced scoliosis and kyphotic patients. Patients with pectus carinatum and pectus excavatum-like chest deformity) - Patients for whom tru cut biopsy is absolutely and relative contraindicated (suspected hydatid cyst or known vascular lesions such as arteriovenous malformation, pulmonary varicose, severe obstructive pulmonary disease, coagulopathy, moderate to severe pulmonary hypertension, ventilator dependence, unilateral pneumectomy) - Patients allergic to local anesthetic drug used for skin and subcutaneous tissue anesthesia - Patients who do not want to participate |
Country | Name | City | State |
---|---|---|---|
Turkey | Trakya University | Edirne |
Lead Sponsor | Collaborator |
---|---|
Trakya University |
Turkey,
Casal-Mourino A, Valdes L, Barros-Dios JM, Ruano-Ravina A. Lung cancer survival among never smokers. Cancer Lett. 2019 Jun 1;451:142-149. doi: 10.1016/j.canlet.2019.02.047. Epub 2019 Mar 6. — View Citation
Heerink WJ, de Bock GH, de Jonge GJ, Groen HJ, Vliegenthart R, Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: meta-analysis. Eur Radiol. 2017 Jan;27(1):138-148. doi: 10.1007/s00330-016-4357-8. Epub 2016 Apr 23. — View Citation
Hiraki T, Mimura H, Gobara H, Shibamoto K, Inoue D, Matsui Y, Kanazawa S. Incidence of and risk factors for pneumothorax and chest tube placement after CT fluoroscopy-guided percutaneous lung biopsy: retrospective analysis of the procedures conducted over — View Citation
Marshall D, Laberge JM, Firetag B, Miller T, Kerlan RK. The changing face of percutaneous image-guided biopsy: molecular profiling and genomic analysis in current practice. J Vasc Interv Radiol. 2013 Aug;24(8):1094-103. doi: 10.1016/j.jvir.2013.04.027. Ep — View Citation
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pneumothorax incidence | Development of pneumothorax after biopsy as a complication | first 24 hours | |
Secondary | Chest tube placement incidence | Incidence of patients needing chest tube after biopsy | Immediately after procedure |
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