Lung Cancer Clinical Trial
Official title:
Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.
Status | Recruiting |
Enrollment | 63 |
Est. completion date | September 1, 2022 |
Est. primary completion date | June 8, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Having a diagnosis of lung cancer - Lung lobectomy operation will be performed - 18 years and older patients - Having an American Society of Anesthesiologists score of 1, 2, 3 - Having approved and signed the informed consent form Exclusion Criteria: - Patients who underwent lobectomy with a diagnosis other than lung cancer - Patients younger than 18 years - Patients with an American Society of Anesthesiologists score of 4 and above - Patients who did not accept informed consent - Patients who refused to participate in the study |
Country | Name | City | State |
---|---|---|---|
Turkey | Bursa Uludag Üniversitesi Tip Fakültesi | Bursa | Nilüfer |
Lead Sponsor | Collaborator |
---|---|
Turkish Society of Anesthesiology and Reanimation |
Turkey,
Cederholm T, Barazzoni R, Austin P, Ballmer P, Biolo G, Bischoff SC, Compher C, Correia I, Higashiguchi T, Holst M, Jensen GL, Malone A, Muscaritoli M, Nyulasi I, Pirlich M, Rothenberg E, Schindler K, Schneider SM, de van der Schueren MA, Sieber C, Valentini L, Yu JC, Van Gossum A, Singer P. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017 Feb;36(1):49-64. doi: 10.1016/j.clnu.2016.09.004. Epub 2016 Sep 14. — View Citation
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Kondrup J, Rasmussen HH, Hamberg O, Stanga Z; Ad Hoc ESPEN Working Group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003 Jun;22(3):321-36. — View Citation
McKenna NP, Bews KA, Al-Refaie WB, Colibaseanu DT, Pemberton JH, Cima RR, Habermann EB. Assessing Malnutrition Before Major Oncologic Surgery: One Size Does Not Fit All. J Am Coll Surg. 2020 Apr;230(4):451-460. doi: 10.1016/j.jamcollsurg.2019.12.034. Epub 2020 Feb 26. — View Citation
Neelemaat F, Kruizenga HM, de Vet HC, Seidell JC, Butterman M, van Bokhorst-de van der Schueren MA. Screening malnutrition in hospital outpatients. Can the SNAQ malnutrition screening tool also be applied to this population? Clin Nutr. 2008 Jun;27(3):439-46. doi: 10.1016/j.clnu.2008.02.002. Epub 2008 Apr 18. — View Citation
Vellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, Albarede JL. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition. 1999 Feb;15(2):116-22. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative complications | dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak | a month after the surgery | |
Primary | Length of stay in the intensive care unit | Length of stay in the intensive care unit | up to 30 days | |
Primary | Length of hospital stay | Length of hospital stay | up to 30 days | |
Primary | Intraoperative hemodynamic complications | dysrhythmia, hypotension, hypertension, hemorrhage | during the procedure | |
Secondary | Oral intake | time to start oral intake and transition to adequate oral intake | up to 30 days | |
Secondary | pH | pH in arterial blood gas evaluation | during the procedure | |
Secondary | bicarbonate | bicarbonate level in arterial blood gas evaluation | during the procedure | |
Secondary | base excess | base excess in arterial blood gas evaluation | during the procedure | |
Secondary | lactate | lactate level in arterial blood gas evaluation | during the procedure | |
Secondary | glucose | glucose level in arterial blood gas evaluation | during the procedure |
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