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Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases — ACHIEVE  

Lung Cancer Clinical Trial

Official title:
High-dose Almonertinib(HS-10296) as First-line Treatment in Patients With EGFR-sensitive Mutations in Advanced NSCLC With Brain Metastases: Prospective, Open-label, Multi-center, Single-arm Clinical Trial

Clinical Trial Summary

This is a prospective, open-label, multi-center, single-arm clinical trial

Clinical Trial Description

This is a prospective, open-label, multi-center, single-arm clinical trial aimed at patients with advanced non-small cell lung cancer (NSCLC) with asymptomatic brain metastases with epidermal growth factor receptor sensitive mutations (EGFRm+) who have not received any systemic treatment To evaluate the effectiveness and safety of high-dose almonertinib mesylate.Eligible patients were included in the high-dose almonertinib treatment group and received oral almonertinib 165 mg once a day. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04808752
Study type Interventional
Source Zhejiang Cancer Hospital
Contact
Status Active, not recruiting
Phase Phase 2
Start date July 9, 2021
Completion date July 15, 2024
View Details
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