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Ethnic/Racial Differences in Metabolism and DNA Adduct Formation

Lung Cancer Clinical Trial

Official title:
Ethnic/Racial Differences in Metabolism and DNA Adduct Formation by 1,3-butadiene

Clinical Trial Summary

The study will investigate the role of 1,3-butadiene metabolic activation and deactivation in lung cancer risk among various ethnic/racial groups. This project will require urine samples from smokers and nonsmokers from the three ethnic/racial groups recruited by the Clinical and Biomarker Core for the analysis of 1,3-butadiene DNA adducts. Data on nicotine intake (urinary TNE) in these subjects as well as in 400 lung cancer cases and 400 controls from Project 1 will be also required for this project.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03421678
Study type Observational
Source Masonic Cancer Center, University of Minnesota
Contact
Status Withdrawn
Phase
Start date October 2020
Completion date June 2023
View Details
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