A Study to Evaluate Clinical Characteristics of Lung Cancer in Patients With Surgeries and Adjuvant Therapies

Lung Cancer Clinical Trial

Official title:

A Multi-centre Real-world Non-interventional Observational Study to Evaluate Clinical Characteristics of the Chinese Patients With Lung Malignant Tumors Who Received Surgeries or Surgeries Plus Adjuvant Therapies

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03421093
• Other study ID #: TSCI-4
• Status: Completed
• Start date: December 1, 2017
• Est. completion date: March 30, 2018

Study information

• Verified date: May 2018
• Source: West China Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study was designed to evaluate effectiveness of the surgeries and adjuvant therapies after surgeries in the patients with lung malignant tumors

Description:

The trial is a multi-centre real-world non-interventional observational study to evaluate effectiveness of the surgeries and adjuvant therapies after surgeries in the patients with lung malignant tumors via a retrospectively review method on the study data on patient demographic/tumor biological characteristics and clinical treatments.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21777
• Est. completion date: March 30, 2018
• Est. primary completion date: March 30, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age >= 18 years old;

• Pathologically diagnosed lung malignant tumors after surgeries;

• Patients with lung surgeries;

• Patients with complete medical health records and follow-up visit information (at least one follow-up visit);

Exclusion Criteria:

• Patients who were not performed with surgeries;

• Pathologically diagnosed patients with benign diseases after surgeries;

Related Conditions & MeSH terms

• Lung Cancer
• Lung Neoplasms

Intervention

Procedure:
• Surgeries
Surgeries or surgeries plus adjuvant therapies

Locations

Country	Name	City	State
China	China PLA General Hospital	Beijing	Beijing
China	China-Japan Friendship Hospital	Beijing	Beijing
China	West China Hospital, Sichuan University	Chengdu	Sichuan
China	First Hospital Affiliated to Zhejiang University	Hangzhou	Zhejiang
China	Jiangsu cancer hospital	Nanjing	Jiangsu
China	Shanghai Chest Hospital	Shanghai	Shanghai
China	Tianjin Chest Hospital	Tianjin	Tianjin
China	Tongji Hospital Affiliated to Huaxi Technology University	Wuhan	Hubei
China	Xi'an Tangdu Hospital	Xi'an	Shaanxi
China	Henan cancer hospital	Zhengzhou	Henan

Sponsors (2)

Lead Sponsor	Collaborator
West China Hospital	LinkDoc Technology (Beijing) Co. Ltd.

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Differences in overall survivals of the patients with surgeries	Differences in perioperative overall survivals and overall survivals of the patients who received surgeries of thoracotomy, video-assistant thoracic surgery or robotic thoracic surgery	2014 - 2017
Other	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by tumor clinical/pathological staging	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by tumor clinical/pathological staging	2014 - 2017
Other	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by location of tumors and tumor sizes	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by location of tumors and tumor sizes	2014 - 2017
Other	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by duration and modes of surgeries	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by duration and modes of surgeries	2014 - 2017
Other	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by type of insurances	Impact factors of patient survival in patients with tumor size =<2 cm who received surgeries as measured by type of insurances	2014 - 2017
Other	Overall survival in the patients with tumor size =< 2cm who received surgeries	Overall survival in the patients with tumor size =< 2cm who received surgeries	2014 - 2017
Other	Impact factors of patient survivals in the patients with N2 lung cancer with surgeries or surgeries plus adjuvant therapies	Impact factors of patient survivals in the patients with N2 lung cancer who received surgeries or surgeries plus adjuvant therapies	2014 - 2017
Other	Overall survival in the patients with N2 lung cancer with surgeries or surgeries plus adjuvant therapies	Overall survival in the patients with N2 lung cancer who received surgeries or surgeries plus adjuvant therapies	2014 - 2017
Other	Impact factors of patient survivals in the patients with small lung cancer with surgeries or surgeries plus adjuvant therapies	Impact factors of patient survivals in the patients with small lung cancer who received surgeries or surgeries plus adjuvant therapies	2014 - 2017
Other	Overall survival in the patients with small lung cancer with surgeries or surgeries plus adjuvant therapies	Overall survival in the patients with small lung cancer who received surgeries or surgeries plus adjuvant therapies	2014 - 2017
Other	Demographic characteristics of the patients with non-small cell lung cancer who were treated with chemotherapies, tyrosine kinase inhibitors, and other adjuvant therapies or were not treated with adjuvant therapies	Demographic characteristics of the patients with non-small cell lung cancer who were treated with chemotherapies, tyrosine kinase inhibitors, and other adjuvant therapies or were not treated with adjuvant therapies as measured by: Age; Gender; Payment types; Insurance types; Smoking history; Complications and symptoms of complications; Respiratory functions; Type of diagnoses	2014 - 2017
Other	Tumor clinical/pathological types	Tumor clinical/pathological types	2014 - 2017
Other	Type of EGFR	Type of EGFR	2014 - 2017
Other	ECOG scores	ECOG scores	2014 - 2017
Other	1-year and 3-year overall survivals	1-year and 3-year overall survivals	2014 - 2017
Primary	Demographic characteristics of the patients with lung malignant tumors who received surgeries	Demographic characteristics of the patients with lung malignant tumors who received surgeries of thoracotomy, video-assistant thoracic surgery or robotic thoracic surgery as measured by: Age; Gender; Payment types; Insurance types; Smoking history; Complications and symptoms of complications; Respiratory functions; Type of diagnoses	2014 - 2017
Secondary	Location of tumors and tumor sizes	Location of tumors and tumor sizes	2014 - 2017
Secondary	Tumor clinical/pathological staging	Tumor clinical/pathological staging	2014 - 2017
Secondary	Type of biomarkers	Type of biomarkers	2014 - 2017