Lung Cancer Clinical Trial
Official title:
The Impact of Trimodal Prehabilitation Strategy on Perioperative Functional Capability and Prognosis of Patients Undergoing Thoracoscopic Lobectomy for Lung Cancer:a Randomized Controlled Trail
Verified date | October 2018 |
Source | Peking Union Medical College Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The process of enhancing an individual's functional capacity to optimize physiologic reserves before an operation to withstand the stress of surgery has been coined prehabilitation. This is a prospective randomized controlled trail, designed to explore if the patients who take thoracoscopic lobectomy for lung cancer will benefit from family trimodal prehabilitation strategy. Trimodal prehabilitation includes exercise, nutrition supplement and physiology management preoperatively. It starts from the day that patients decide to take the surgery until the day before surgery, lasting 2~3 week in our hospital. And we follow-up patients until 8 weeks after surgery to investigate if trimodal prehabilitation strategy can improve the postoperative functional recovery,reduce complications and improve prognosis.
Status | Completed |
Enrollment | 100 |
Est. completion date | December 1, 2017 |
Est. primary completion date | December 1, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: 1. Outpatient of thoracic surgery department in Peking Union Medical College Hospital 2. From 18 y/o to 70 y/o 3. Suspected of lung cancer 4. Decide to take the elective thoracoscopic surgery in Peking Union Medical College Hospital Exclusion Criteria: 1. Refuse or fail to cooperate the study (due to any reason) 2. ASA grade = III 3. Unable to tolerate prehabilitaion strategy (including exercise guide, whey protein and psycho-relaxation exercise) 4. Other severe cardio-pulmonary diseases that would affect the 6MWD |
Country | Name | City | State |
---|---|---|---|
China | Peking Union Medical College Hospital | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
Peking Union Medical College Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 6-minute-walking-distance (6MWD) | Use 6-minute-walking-distance (6MWD) to evaluate the physical functional capability objectively. | 4 weeks postoperatively | |
Secondary | Quality of Life Scale | Evaluate the intermediate phase of recovery | the 1st, 2nd and 3rd day postoperatively | |
Secondary | the version 2 of 12-items Short Form Health Survey(SF 12-v2 | Evaluate the late phase physical and mental capability recovery after surgery | 4 weeks postoperatively | |
Secondary | WHO disability assessment schedule 2.0 (WHODAS 2.0 | Evaluate the global disability in the late phase of recovery | 4 weeks postoperatively | |
Secondary | Hospital Anxiety and Depression Scale (HADS) | Evaluate the late phase mental capability recovery after surgery | 4 weeks postoperatively |
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