Lung Cancer Clinical Trial
Official title:
Determination of the Prognostic and Predictive Value of the Cancer Antigen-125 (CA-125) Marker in Lung Cancer Monitoring
The tumor associated CA-125antigen for diagnosis and follow-up of ovarian cancer was well
defined. Increased serum CA125 level may have many diagnoses other than ovarian cancer,
including breast, colorectal and lung cancer. 80% lung cancer patients were diagnosed at
advanced stage. Malignant pleural effusion secondary to lung cancer represented the
condition of cancer cell involved pleura.
The CA-125 level may reflect the extent of tumor involved in pleura (tumor burden), it could
be correlated with the prognosis. This study was performed to examine the properties of
CA-125 by measuring pleural and blood CA-125 levels in lung cancer with or without malignant
pleural effusion; meanwhile to examine whether the rate of decline in CA 125 during primary
therapy as a surrogate indicator for survival.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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