Lung Cancer Clinical Trial
Official title:
Perioperative Rehabilitation in Operation for Lung Cancer
Background: Improved surgical techniques combined with effective adjuvant chemotherapy, has
led to a better survival in individuals with NSCLC. The treatment of NSCLC and other cancer
diseases are after all still complex and potentially lethal.
Study aim: The rationale for the study PROLUCA is to identify the optimal timing of exercise
to improve recovery after surgery in patients operated for lunge cancer with focus on
physical capacity and quality of life.
Who can participate? Patients above 18 years and diagnosed with lung cancer and referred for
operation. Participation in this study is not possible if the participants by a doctor are
advised not to do strenuous exercise.
What does the study involve? The intervention consists of a combination of (1) exercise
before surgery and (2) exercise after surgery for lung cancer.
1. Exercise before surgery is a home-based exercise program is individually designed and
must be performed for at least 30 minutes every day until surgery. The home-based
exercise program varies in length due to number of days until surgery, and the
intention is not exceed 14 days.
2. The exercise initiated two weeks and 6 weeks after surgery consists of a 12 weeks
rehabilitation program and three individual counseling sessions. Special needs in terms
of smoking cessation, nutritional counseling or patient education, this is also
offered. The exercise consists of individually prepared supervised strength - and
fitness exercise in a team, two sessions of 60 minutes/week.
What interventions will be compared? A home-based post-operative exercise program, combined
with exercise initiated two weeks after surgery, will be compared with usual care (exercise
initiated six weeks after surgery).
Will all participants receive the same treatment?
By draw it is decided which of the 4 groups the participants will attend to in the study:
- Group 1: Home-based exercise before surgery and rehabilitation initiated as early as
two weeks after surgery
- Group 2: Home-based exercise before surgery and rehabilitation initiated six weeks
after surgery
- Group 3: Rehabilitation initiated as early as two weeks after surgery
- Group 4: Rehabilitation initiated six weeks after surgery (Usual practice as control
group) What are the possible benefits and risks of participating? There are no risks or
side- effects of participating other than muscle soreness and exercise is beneficial
when it comes to recover from an operation from lung cancer.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Caregiver, Outcomes Assessor), Primary Purpose: Treatment
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