Lung Cancer Clinical Trial
— PDT RegistryOfficial title:
Photodynamic Therapy (PDT) Oncology Registry
NCT number | NCT01842555 |
Other study ID # | R16-3560 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | November 2012 |
Est. completion date | December 30, 2024 |
Verified date | August 2018 |
Source | Main Line Health |
Contact | Patsy Skabla, PA |
SkablaP[@]mlhs.org | |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
The data elements for the PDT Registry project include virtually all the elements in the standard hospital-based cancer registry record, although in some cases at a finer level of detail. All data points should be found in the participant's medical record. The principal difference between the PDT Registry data set and that collected by the registries is the inclusion of more information specific to PDT.
Status | Recruiting |
Enrollment | 1000 |
Est. completion date | December 30, 2024 |
Est. primary completion date | November 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18 years of age or older, male or female, diagnosed with cancer and is undergoing or has undergone Photodynamic Therapy (PDT). - Patients must have undergone PDT with Photofrin® at a participating institution. - Patients scheduled to undergo PDT with Photofrin® - Cancer patients receiving some or all primary care (e.g.,cancer-directed surgery, systemic therapy, radiation therapy, palliative care)in the participating institution. - Cancer patients with a history of any type of cancer who have been no evidence of disease(for five years but without a history of distant metastases or evidence of relapse if they meet the previous criteria). Exclusion Criteria: - Cancer patients who present to the participating institution with a diagnosis of a simultaneous second primary. - Cancer patients receiving all primary cancer care (e.g., cancer-directed surgery, chemotherapy, targeted therapy, radiation therapy, palliative care) outside of participating institution. - Patients treated with photosensitizers other than Photofrin® |
Country | Name | City | State |
---|---|---|---|
United States | Main Line Health, Lankenau Medical Center | Wynnewood | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Main Line Health | Pinnacle Biologics Inc. |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | A Photodynamic Therapy (PDT) research repository and de-identified registry | Participating sites will be able to utilize aggregate, de-identified data to perform research on PDT, the patients receiving PDT, and their outcomes and complications after the procedure. Data collected includes the following: Table 1. Outline of Data Elements in the PDT Registry Patient Visit Form- Demographics Patient Identification Number Institution Number Study Type Surgeon ID Date of Birth Age at PDT Racial Background Gender Tobacco Use Alcohol Use Vital Status Pre-Treatment Primary Site Clinical Sta |
Up to 3 years | |
Secondary | Survival following palliative and non-palliative PDT | calculated by date of PDT treatment and date of death (where applicable) | Up to 3 years | |
Secondary | Short and long term efficacy of PDT in presenting symptom improvement | Quality of Life Score before and after PDT | Up to 3 years | |
Secondary | Complications after PDT | 30-day mortality (yes/no), length of stay in hospital (number of days), assessment of PDT-related complications (ex: phototoxic reaction (yes/no), urgent re-bronchoscopy (yes/no)) | up to 3 years after |
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