A Protocol of Irinotecan for Carcinoma of the Lung

Status Withdrawn

Clinical Trial Summary

The goal of this trial is to demonstrate the potential clinical benefit of irinotecan chemotherapy in patients with a specific NSCLC phenotype, ISG15-positive. The use of irinotecan in subjects with ISG15-positive NSCLC will be associated with an improved rate of clinical benefit (objective response, disease stability, and time to progression) compared to historical controls that were not previously selected for ISG-15 expression.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01654081
Study type	Interventional
Source	University of Kentucky
Contact
Status	Withdrawn
Phase	Phase 2
Start date	October 2013
Completion date	May 2014

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