Lung Cancer Clinical Trial
Official title:
Molecular Characterization of Lung Cancer: A Collaboration With the Cancer Genome Atlas Project (TGCA)
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help
doctors learn more about changes that occur in DNA and identify biomarkers related to
cancer.
PURPOSE: This research trial studies tissue samples from patients with non-small cell lung
cancer.
OBJECTIVES:
- To identify and characterize single nucleotide variations (SNVs) in non-small cell lung
cancer (NSCLC) specimens.
- To identify and characterize structural variations in the genomes of NSCLC specimens.
- To identify and characterize other genomic alterations including, but not limited to,
expression profiling and methylation.
OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide
variations, structural variations in the genomes, and other genomic alterations including,
but not limited to, gene expression profiling and methylation. Clinical data related to
disease, treatment, and recurrence from each patient sample is also collected.
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