Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia

Lung Cancer Clinical Trial

Official title:

Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT00935571
• Other study ID #: 20090708
• Status: Active, not recruiting
• Phase: N/A
• First received: July 8, 2009
• Last updated: July 8, 2009
• Start date: October 2007
• Est. completion date: September 2009

Study information

• Verified date: July 2009
• Source: Asan Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Food and Drug AdministrationKorea: Ministry for Health and Welfare
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.

Description:

Thoracotomy is one of the most painful surgical incisions. It has been shown that 5-80% of patients still suffer from thoracic pain 2-3 months after surgery and the international association for the study of pain (IASP) defines postthoracotomy pain syndrome (PTTS)as pain that recurs or persists at least 2 months after surgical procedure. Previous reports have shown that the incidence of PTTS varies according to preoperative pain, pain intensity, sex, and types of procedure. However, little is known about the effect of the type of anesthesia to postthoracotomy pain.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 400
• Est. completion date: September 2009
• Est. primary completion date: June 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients undergo elective thoracotomy of lung surgery

Exclusion Criteria:

• emergency operation age under 18 years patients with unstable hemodynamics

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Lung Cancer
• Lung Neoplasms
• Neoplasms, Lung

Intervention

Drug:
• propofol, remifentanil, sevoflurane
Propofol: using target controlled infusion (TCI); 1-3ug/ml remifentanil: using TCI by 5-20 ng/ml sevoflurane: 2-3volume% (1-2 MAC)

Locations

Country	Name	City	State
Korea, Republic of	Department of Anesthesiology and Pain Medicine, University of Ulsan College of Medicine, Asan Medical Center	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Asan Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (1)

Gotoda Y, Kambara N, Sakai T, Kishi Y, Kodama K, Koyama T. The morbidity, time course and predictive factors for persistent post-thoracotomy pain. Eur J Pain. 2001;5(1):89-96. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of pain		3 and 6 months later after operation	No
Secondary	pain characters		3 and 6 months later after operation	No