Lung Cancer Clinical Trial
Official title:
Amgen Protocol 20060534 - A Phase 1b/2 Trial of AMG 479 or AMG 102 in Combination With Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer
This trial is titled "A Phase 1b/2 trial of AMG 479 or AMG 102 with Platinum-Based
Chemotherapy as First-Line Treatment for Extensive Stage Small-Cell Lung Cancer (SCLC)."
Part 1, the phase 1b portion of this study, is a multicenter, open-label investigation to
identify safe dose levels of either AMG 102 or AMG 479 in combination with etoposide plus
cisplatin or carboplatin in subjects with previously untreated extensive stage SCLC.
Part 2, the phase 2 portion of this study, is a multicenter, double-blind, 3-arm
investigation to evaluate overall survival of either AMG 102 or AMG 479 in combination with
platinum-based chemotherapy.
n/a
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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