Quantifying Lung Tumor Movement Under Deep Inspiration Breath Holds

Lung Cancer Clinical Trial

Official title:

Quantifying Lung Tumor Movement Under Dep Inspiration Breath Holds

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00643370
• Other study ID #: LU-23980
• Status: Completed
• Phase: N/A
• First received: March 24, 2008
• Last updated: February 12, 2016
• Start date: April 2008

Study information

• Verified date: August 2011
• Source: AHS Cancer Control Alberta
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Observational

Clinical Trial Summary

Radiotherapy is a common treatment for lung cancer. One Challenge of delivering radiation treatment to lung tumors accurately is tumor movement which occurs as a patient breathes. In some situations, tumors move enough during breathing so that some or all of the tumor may be missed by a radiation treatment. One way to decrease the amount a lung tumor moves during radiotherapy treatments is for patients to held their breath briefly during a radiation treatment. By doing this, a patient's lung tumor may not move as much as it would during regular breathing. In this study, the investigators aim to study patients with lung cancers which move during breathing. Patients will be asked to hold their breath after inspiration while a CT scan of their lung tumor is obtained. The purpose of this study is to study how much less patients' lung tumors move when they hold their breath

Recruitment information / eligibility

• Status: Completed
• Enrollment: 8
• Est. primary completion date: January 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• biopsy confirmed primary lung cancer

• undergoing radiotherapy or chemoradiotherapy

• able to perform adequate deep inspiration breath hold

• patients of childbearing potential must practice adequate contraception

• signed study-specific informed consent form

Exclusion Criteria:

• unable to perform adequate deep inspiration breath hold

• prior tumor resection

• prior chest or neck RT

• pregnant

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Lung Cancer

Intervention

Other:
• CT scan of the chest under deep inspiration breath hold
computed tomography scan of the chest under dep inspiration breath hold conditions

Locations

Country	Name	City	State
Canada	Cross Cancer Institute	Edmonton	Alberta

Sponsors (2)

Lead Sponsor	Collaborator
AHS Cancer Control Alberta	Cross Cancer Institute

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	tumor movement		12 months	No