Lung Cancer Clinical Trial
Official title:
Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
Verified date | June 2024 |
Source | Stanford University |
Contact | Eyiwunmi Laseinde |
Rad-onc-ccto[@]lists.stanford.edu | |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The purpose of this study is to identify and confirm new blood and tissue markers for prognosis and tumor hypoxia. Tumor hypoxia, or the condition of low oxygen in the tumor, has been shown to increase the risk of tumor spread and enhance tumor resistance to the standard treatment of radiation and chemotherapy in head and neck and lung cancers. We have recently identified several proteins or markers in the blood and in tumors (including osteopontin, lysyl oxidase, macrophage inhibiting factor and proteomic technology) in the laboratory that may be able to identify tumors with low oxygen levels or more aggressive behaving tumors.
Status | Recruiting |
Enrollment | 600 |
Est. completion date | April 30, 2025 |
Est. primary completion date | April 30, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Histologically confirmed squamous cell carcinoma of the head and neck sites or non-small cell lung cancer, or relatives of patients with histologically confirmed squamous cell carcinoma of the head and neck. - Able to sign a Stanford IRB approved consent form Exclusion criteria: - Refuse or unable to sign an IRB approved consent form. - Refuse to be contacted in the future for follow up. |
Country | Name | City | State |
---|---|---|---|
United States | Stanford University School of Medicine | Stanford | California |
Lead Sponsor | Collaborator |
---|---|
Stanford University | National Institutes of Health (NIH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Identification of Secreted Markers for Tumor Hypoxia through tissue collection | before therapy, weekly during therapy |
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