Lung Cancer Clinical Trial
Official title:
Adjuvant Treatment of Non Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare cisplatin and etoposide with no chemotherapy
in treating patients who have stage I, stage II, or stage IIIA non-small cell lung cancer
that has been surgically removed.
OBJECTIVES:
- Assess the efficacy of the combination of cisplatin and etoposide after radical surgery
in prolonging the relapse free and overall survival for stages I, II, and IIIA
non-small cell lung cancer.
OUTLINE: This a randomized study (treatment vs no treatment). Patients are stratified
according to sex and to stage of disease (I vs II vs IIIA).
Patient receives cisplatin and etoposide on days 1-3, every 28 days, for 3 cycles. Patient
may receive radiation therapy after surgery at the discretion of the physician.
PROJECTED ACCRUAL: Approximately 750 patients will be accrued over 3 years.
;
Allocation: Randomized, Primary Purpose: Treatment
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