Safety Study of Stem Cell Transplant to Treat Limbus Insufficiency Syndrome

Limbus Corneae Insufficiency Syndrome Clinical Trial

Official title: Advanced Therapy for Ocular Surface Reconstruction. Allogenic Limbus Epithelial Stem-cell Transplant vs Bone Marrow Mesenchymal Stem-cell Transplant in Limbus Insufficiency Syndrome. Double-masked Randomized Trial

Status Completed

Clinical Trial Summary

The purpose of the study is to determine whether allogenic bone marrow stem cell transplant is safe and effective in the treatment of limbus insufficiency syndrome versus allogenic limbus stem cell transplant.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Limbus Corneae Insufficiency Syndrome
• Syndrome

• NCT number: NCT01562002
• Study type: Interventional
• Source: Instituto Universitario de Oftalmobiología Aplicada
• Status: Completed
• Phase: Phase 1/Phase 2
• Start date: March 2012
• Completion date: December 2014