Li-Fraumeni Syndrome Imaging Study

Status Enrolling by invitation

Clinical Trial Summary

Li-Fraumeni Syndrome (LFS) is a cancer predisposition disorder in which most affected individuals develop cancer during their lifetime. The majority of LFS patients carry a mutation in a gene called TP53, whose normal function is to control cell growth and prevent cells with damaged DNA from becoming cancerous. There is currently no way to determine when, where or what type of tumour will develop. This project will use novel techniques utilizing magnetic resonance imaging (MRI) to determine how sensitive they are at detecting very small tumors and how specific they are in terms of distinguishing malignant tumors from benign tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03176836
Study type	Interventional
Source	The Hospital for Sick Children
Contact
Status	Enrolling by invitation
Phase	N/A
Start date	June 20, 2016
Completion date	December 31, 2025

View Details

See also
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