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Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome — SIGNIFY  

Li-Fraumeni Syndrome Clinical Trial

Official title:
Magnetic Resonance Imaging Screening In Li Fraumeni Syndrome: An Exploratory Whole Body MRI Study

Clinical Trial Summary

This study is aimed at exploring the use of whole body MRI for early cancer detection in TP53 mutation carriers and population controls, with the hypothesis that more cancers will be detected in the TP53 mutation carrier group. A secondary end-point will be the number of incidental findings detected and subsequent investigations required. A series of questionnaires will be used to assess the psychological impact of screening on both the study and control group.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01737255
Study type Observational
Source Institute of Cancer Research, United Kingdom
Contact
Status Completed
Phase
Start date October 2012
Completion date December 2017
View Details
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