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Lesions clinical trials

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NCT ID: NCT02979509 Completed - Gastroenterology Clinical Trials

Evaluation of Diagnostic Yield of EUS-Guided Tissue Sampling

Start date: June 2016
Phase:
Study type: Observational

All patients will receive standard medical care and no experimental interventions will be performed. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a well-established procedure commonly used for the investigation of lesions within or adjacent to the gastrointestinal (GI) lumen (i.e. pancreas, liver, mediastinal masses, left adrenal gland, lymph nodes, and subepithelial lesions). EUS-guided tissue sampling has been commonly performed with different size and types of aspiration and core biopsy needles.

NCT ID: NCT00923780 Completed - Lesions Clinical Trials

Evaluation of Blood Vessel Formation in Endocrine Tumors

Start date: January 5, 2007
Phase: N/A
Study type: Observational

Background: - Tumors depend on blood vessels to provide the nourishment that allows them to grow. - Thyroid, parathyroid, adrenal gland and pancreatic neuroendocrine tumors are among the tumors that contain the most blood vessels. Thus, endocrine tumors are important for the study of new blood vessel formation in tumors. Objectives: -To obtain tissues from endocrine tumors for examination to determine how they differ from normal tissue. Eligibility: -Patients who are scheduled for surgery to remove an endocrine tumor, those in or around the thyroid, parathyroid, adrenal gland, pancreas, or any neuroendocrine tissue. Design: - Tissues will be obtained from patients during surgery to remove thyroid, parathyroid, adrenal, pancreas, or neuroendocrine tumors. - About 400 patients will be enrolled in the study over a period of 5 years.

NCT ID: NCT00861172 Completed - Multiple Sclerosis Clinical Trials

Longitudinal (Weekly) Follow-up of Active Plaques in Multiple Sclerosis With 3 Teslas Multi-modality MRI Using Diffusion, Perfusion, Venography and Proton Spectroscopy

IRM 3T-SEP
Start date: February 2009
Phase: N/A
Study type: Interventional

It is difficult to determinate prognostic criteria of Multiple Sclerosis with conventional MRI insofar as physiopathology is not well-known: the precise sequences of events leading to plaque formation and axonal injury are still not completely understood. Some elements involved in plaque formation can be studied thanks to MR techniques (cerebrospinal fluid and periveinular spaces, neuronal injury, microglia, and cerebral microcirculation's dysfunction). This study aims at giving a better understanding of MS plaques' physiopathology, using data from modern MRI through a longitudinal followed up with weakly MR 3T examination.