Heart Failure Clinical Trial
Official title:
Resynchronization in Paced Heart Failure Patients With ICD Indication
Today patients with a Cardiac Resynchronization Therapy (CRT) indication usually receive 2
ventricular leads, right ventricular (RV) apex and left ventricular (LV) (postero-) lateral,
gaining a responder rate of approximately 70%. However, the physiological agitation of the
left ventricle takes place over two pathways. Therefore single point stimulation might be
insufficient for a dilated, insufficiently and asynchronously contracting left ventricle,
resulting in either insufficient or no response to the therapy.
In the "CRT ICD Dual LV" study the patients receive a second LV lead in an anterior vein.
When this lead is placed, temporary dual LV stimulation is started. To assess the
effectivity of the dual LV lead stimulation intraoperatively a LV dp/dt-pressure measurement
is taken. If there is an increase in LV dp/dt, the patients will be stimulated with both
leads permanently. If not they will be stimulated conventionally.
The patients participating in this study are monitored for 12 months after implantation.
n/a
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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