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Labor, Induced clinical trials

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NCT ID: NCT03407625 Completed - Pregnancy Clinical Trials

Foley Bulb With Oral Misoprostol for Induction of Labor

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Induction of labor is associated with increased cesarean delivery rates, particularly in women with an unfavorable cervix. Both pharmacologic and mechanical methods are utilized for cervical ripening and labor induction. Evidence on the safety and effectiveness of various mechanical and pharmacologic methods of cervical ripening and labor induction is abundant, and yet the majority of clinical trials evaluate time to delivery, rather than mode of delivery. This is a prospective, cluster-randomized clinical trial to compare a standard method of induction at our institution (oral misoprostol) with an alternative, commonly used combination method of oral misoprostol and transcervical foley bulb in women with term pregnancies requiring induction of labor.

NCT ID: NCT03140488 Completed - Obesity Clinical Trials

Oxytocin Dosage to Decrease Induction Duration

OPS
Start date: June 5, 2017
Phase: Phase 4
Study type: Interventional

This is a randomized controlled trial in which women are allocated either 'high dose' or 'low dose' oxytocin infusions for induction of labour. The randomization is stratified by maternal body mass index.

NCT ID: NCT01962831 Completed - Obesity Clinical Trials

Randomized Controlled Trial: Induction of Labour of Obese Women With Dinoprostone or Single Balloon Catheter

Start date: October 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the efficacy of single balloon foley catheters to dinoprostone for the induction of labour of obese women. The investigators suspect that women assigned to the foley group will have a shorter induction to delivery time than women in the dinoprostone group.

NCT ID: NCT00992524 Completed - Labor, Induced Clinical Trials

Oral Titrated Misoprostol for Induction of Labour

OTISMISO
Start date: November 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare effectiveness and safety of an oral titrated solution of misoprostol with vaginal misoprostol for induction of labour with an alive fetus.

NCT ID: NCT00843362 Completed - Cervical Ripening Clinical Trials

24-Hour Vaginal Dinoprostone Pessary Versus Gel for Labour Induction

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The aim of induction of labour is to initiate labour when maternal and fetal conditions necessitate delivery before the onset of spontaneous contractions. Prostaglandins are widely used for induction of labour, and can be administered orally, vaginally, intracervically, endovenously and by extra-amniotic or intra-amniotic routes. Dinoprostone is one of the synthetic prostaglandins most commonly used to achieve cervical ripening and labour induction, and can be administered as tablets, suppositories, gel (vaginal and intracervical) or as a controlled-release intravaginal pessary. The controlled-release pessary has some potential advantages: a single application is required; the insert is easily administered and can be removed as soon as labour starts or if complications ensue. Studies comparing the dinoprostone vaginal insert to other prostaglandin formulations have shown variable results, probably influenced by drug administration regimens, indications for induction, and cervical conditions of the women. The purpose of this study is to assess the efficacy of the induction of labour using dinoprostone in patients with an unfavourable cervix, and to compare the efficacy and the cost of 24-hours controlled-release dinoprostone pessary and intravaginal dinoprostone gel.

NCT ID: NCT00545194 Completed - Cervical Ripening Clinical Trials

Cervical Ripening Before Induction of Labour at Term: a Randomised Comparison of Prostin vs Propess

Start date: January 2002
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare two different preparation

NCT ID: NCT00465998 Completed - Pregnancy Clinical Trials

Study of Ultrasound Imaging to Predict Time and Outcome in Pregnancies With Induced Labor

Start date: January 2006
Phase: N/A
Study type: Observational

The aim of the study was to evaluate any possible associations between engagement and position of the fetal head and the outcome of labor in women with induced labor, and to compare the value of ultrasound measurements in predicting the time from induction to delivery and operative deliveries.

NCT ID: NCT00393731 Completed - Labor, Induced Clinical Trials

A Randomized, Control Trial for Preinduction Cervical Ripening

Start date: January 2004
Phase: Phase 2
Study type: Interventional

The goal of this study is to compare the vaginal delivery rates in women undergoing induction of labor with an unripe cervix between oxytocin induction alone and preinduction cervical ripening with prostaglandin El (misoprostol). Secondary goals are to measure and compare the time intervals to delivery between the two methods.

NCT ID: NCT00366951 Completed - Cervical Ripening Clinical Trials

A Randomized Study on Comparing the Efficacy of Foley Catheter and Extraamniotic Saline Infusion for Labor Induction

Start date: April 2004
Phase: N/A
Study type: Interventional

Our purpose was to compare the efficacy and safety of Foley catheter with oxytocin and extraamniotic saline infusion with oxytocin for induction of labor requiring cervical ripening.

NCT ID: NCT00308711 Completed - Cervical Ripening Clinical Trials

Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor

Start date: April 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the misoprostol vaginal insert (50 mcg and 100 mcg) can safely and effectively speed time to vaginal delivery compared to Cervidil (R) in women who need to have cervical ripneing and induction of labor.