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Labor, Induced clinical trials

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NCT ID: NCT05885087 Completed - Labor, Induced Clinical Trials

'Extended Balloon Catheter' Labour Induction; a Single Arm Pilot Trial'

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The overall aim of the single arm pilot study was to assess the effectiveness, safety and acceptance of the 'extended balloon catheter' as a method of induction of labour in women receiving care at Princess Marina Hospital(PMH) in Gaborone, Botswana. The main questions it aimed to answer were whether 'extended balloon catheter' is an effective method of labour induction, whether it results in increased adverse events for the mother and baby and whether it is associated with increased mother satisfaction. Participants were assessed as having a favourable cervix using the modified Bishop score of equal to or more than 7. Three Foley balloon catheters attached side by side were inflated with 60mls each and a gentle traction of 250mls water applied. Delivery interval (time of induction to time of delivery), mode of delivery and Apgar scores were recorded. Adverse maternal and neonatal outcomes were recorded. Participants' satisfaction with the method of induction was assessed using a descriptive scale.

NCT ID: NCT05874024 Completed - Labor, Induced Clinical Trials

Induction of Labour With a Double Balloon Catheter

Start date: January 1, 2021
Phase:
Study type: Observational

The objective of this study is to provide a comprehensive analysis of various time intervals (1:1). In addition to evaluating the time interval until delivery after completion of induction, the study also aims to investigate the rate of vaginal births and the type of combination therapy used (including the method of implementation and subsequent induction).

NCT ID: NCT05838313 Completed - Patient Preference Clinical Trials

Should I Have an Elective Induction?

SELECTION
Start date: March 22, 2023
Phase: N/A
Study type: Interventional

The goal of the proposed study is to perform a pilot test of a patient-centered decision support tool to help pregnant people and providers work together in making informed, shared decisions regarding whether or not to opt for elective IOL at 39 weeks gestation

NCT ID: NCT05109247 Completed - Labor, Induced Clinical Trials

Prediction of Spontaneous Onset of Labor at Term

PREDICT
Start date: August 22, 2019
Phase:
Study type: Observational [Patient Registry]

The study intends to develop a predictive model of spontaneous onset of labor between 39 and 41 weeks of pregnancy in women carrying singletons and without indication of delivery before this date. The main hypothesis is that a combination of clinical, ultrasonographic, biochemical and/or biophysical variables will allow to differentiate women who will spontaneously trigger their labors from those who will require an induction by the term of their pregnancies. A tool of this kind should aid in the individualization of the management of the final weeks of pregnancy and, at the light of recent evidence, provide support to the decision-making processes.

NCT ID: NCT05100264 Completed - Labor, Induced Clinical Trials

Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction

Start date: October 29, 2021
Phase: N/A
Study type: Interventional

Acidification of vaginal pH has been proposed as a potential factor that could help increase the efficacy of vaginal prostaglandins in labor induction. The aim of the present randomized controlled trial is to evaluate the impact of an acidic vaginal pH on the progress of labor induction with dinoprostone (Prostaglandin E2 - PGE2) vaginal tablet.

NCT ID: NCT04755218 Completed - Pregnancy Clinical Trials

Labor Induction With Oral Versus Vaginal Misoprostol

Start date: May 24, 2021
Phase:
Study type: Observational

This study will compare vaginal and oral misoprostol, to determine whether a vaginal misoprostol regimen achieves a higher vaginal delivery rate in a real-world, high-volume setting, and whether this regimen reduces time and oxytocin need on a high-volume Labor and Delivery unit at Parkland Hospital. Our primary hypothesis is that among women with singleton, term pregnancies, cervical dilation 2cm or less, and indicated labor induction, the rate of vaginal delivery is significantly increased when a standardized vaginal misoprostol regimen is used, compared with a standardized oral misoprostol regimen.

NCT ID: NCT04746248 Completed - Labor, Induced Clinical Trials

Outpatient Labor Induction Using Oral Misoprostol in Norway

LINO
Start date: March 25, 2021
Phase: N/A
Study type: Interventional

The rate of labor induction has been steadily increasing over the last years, both worldwide and in Norway. Norwegian women are hospitalized when prostaglandins are used to induce labor. In Denmark, a neighboring country to Norway, women have been offered outpatient induction of labor using oral misoprostol for several years. The overall aim of this study is to investigate if outpatient induction of labor is beneficial in a Norwegian setting. This includes: 1. To investigate the clinical outcomes and feasibility of inducing in an outpatient setting compared to an inpatient setting in Norway 2. To explore low-risk nulliparous women's experiences of labor induction in inpatient and outpatient settings. This is a non-randomized prospective pilot- and feasibility study, collecting data from electronical records. In addition, the study participants are invited to write a diary during the labor induction process and a questionnaire six weeks postpartum. Eligible patients include low-risk nulliparous women induced with low-dose oral misoprostol.

NCT ID: NCT04731896 Completed - Labor, Induced Clinical Trials

Early Versus Late Amniotomy During Labor Induction in Women With Bishop's Score of ≥ 6

Start date: February 8, 2021
Phase: N/A
Study type: Interventional

Labor induction is the stimulation of uterine contractions during pregnancy, before labor begins on its own to achieve a vaginal birth. A health care provider might recommend labor induction for various reasons: primarily when there's concern for a mother's health or a baby's health. Combined with oxytocin infusion, amniotomy is commonly used in the induction of labor. However the perfect timing of amniotomy is still unknown. The aim of this study is to determine whether the early amniotomy followed by oxytocin, or initiating induction of labor with oxytocin followed by late amniotomy, is effective to reach active phase of labor.

NCT ID: NCT03928600 Completed - Cervical Ripening Clinical Trials

Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Labor induction is a common pregnancy procedure worldwide. Both mechanical and pharmacologic agents are used for induction of labor. These agents reduce the incidence of cesarean delivery in women undergoing induction. Opposite to old studies of cervical ripening, some recent studies have shown promise in reducing labor time and risk of cesarean delivery with combination methods. The effectiveness of this procedure is of major clinical importance and has a large impact in our quotidian practice. The objective is to compare the effectiveness of a combined new method to current guidelines of our department

NCT ID: NCT03665688 Completed - Labor, Induced Clinical Trials

Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S®

HOMECARE
Start date: November 7, 2018
Phase: N/A
Study type: Interventional

The target population for our study is women who present for induction of labor. If there is a decision by the obstetrical team to place a mechanical dilator for cervical ripening, the obstetrical team will notify the research staff so that the patient may be screened for the study. If the subject is eligible for the trial, written informed consent will be obtained by person-to-person contact. The PI, study coordinator, or a collaborator will be responsible for the informed consent procedure. After informed consent is obtained and Dilapan-S is placed, the patient will be randomized to the Outpatient or the Inpatient group.