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Knee clinical trials

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NCT ID: NCT05924698 Completed - Knee Clinical Trials

Blood Flow Restriction Therapy Combined With Neuromuscular Electrostimulation in Amateur Female Soccer Players

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

The objective is to know the effects of Neuromuscular Electrical Stimulation (NMES) and its combination with Blood Flow Restriction (BFR) Therapy in healthy amateur female soccer players.

NCT ID: NCT05332717 Completed - Clinical trials for Sleep Initiation and Maintenance Disorders

TKA Melatonin and Sleep Quality

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

This randomized controlled trial (RCT) will compare the effects of melatonin vs. placebo in patients undergoing primary total knee arthroplasty (TKA). This RCT aims to study the effects melatonin has on sleep quality after TKA. Patients will be blinded to their respective groups and will be instructed to take either 5mg melatonin or a placebo pill (Vitamin C) for 6 weeks postoperative. Sleep quality surveys will be administered preoperatively and post-operative week 6, 90-days and 1 year. Poor sleep quality is a common issue faced by patients undergoing TKA. The goal of this study is see if melatonin can improve postoperative sleep quality, and if so, does improved sleep quality correlate to improvements in other postoperative outcomes.

NCT ID: NCT04694625 Completed - Knee Clinical Trials

Structured Rehabilitation Program for Patients With Total Knee Replacement

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

This study will be a randomized controlled trial. This study will be conducted in Horizon Hospital Lahore. A sample size of 26 patients will be taken. Patients will be divided into two groups by lottery method. Group A will be treated with Structured Rehabilitation program along with conventional physiotherapy while Group B will be treated with conventional physiotherapy only. Both groups will receive treatment for 4 weeks,3 sessions per week. The outcome measures Numeric pain rating scale(NPRS),6 minutes' walk test and Womac scale will be measured at baseline and at the end of 4th week. Data will be analyzed by SPSS 25.

NCT ID: NCT04612036 Completed - Knee Osteoarthritis Clinical Trials

In Vivo Kinematics for Subjects With Smith & Nephew Journey II BCS TKA, Journey II CR TKA, Or Journey II XR TKA

Start date: October 22, 2020
Phase:
Study type: Observational

The objective of this study is to determine and compare the in vivo kinematics and vibroarthrography (VAG) signals for subjects implanted with Journey II Bi-Cruciate Stabilized (BCS), CR (Cruciate Retaining), and Bi-Cruciate Retaining (XR) TKAs.

NCT ID: NCT04564053 Completed - Osteoarthritis Clinical Trials

Study of Safety, Tolerability and Pharmacokinetics of LNA043 in Japanese Osteoarthritis Participants

Start date: September 23, 2020
Phase: Phase 1
Study type: Interventional

The objective of this study was to determine the safety, tolerability and pharmacokinetics after single ascending dose of LNA043 in Japanese participants with osteoarthritis of the knee.

NCT ID: NCT04496440 Completed - Knee Osteoarthritis Clinical Trials

An Attempt to Find Out Root Cause of a Pain Producing Knee Disease

Start date: March 23, 2017
Phase:
Study type: Observational

This study was focused on a type of arthritis (knee) in which patients develop pain with disabilities in sitting and walking etc. In advance stage the person is bereft of his/her personal physical activities. The prevalent treatment is temporary and dis-satisfactory. A new treatment was designed and a trial was conducted on 125 patients (100 in the trial group, 25 in the control group) for a duration of six months.

NCT ID: NCT04321356 Completed - Knee Osteoarthritis Clinical Trials

Analysis of Competitive Posterior Cruciate Retaining (PCR) and Posterior Stabilized (PS) Total Knee Arthroplasty (TKA)

Start date: February 24, 2020
Phase:
Study type: Observational

The purpose of the study is to acquire kinematic in vivo fluoroscopy data from subjects who were implanted with Stryker Posterior Cruciate Retaining (PCR) , Stryker Posterior Stabilized (PS), Zimmer PCR, and Zimmer PS Total Knee Arthroplasty (TKAs). Our lab has previously collected data for the Smith & Nephew PCR, bi-cruciate retaining (BCR), and bi-cruciate stabilized (BCS) TKA.

NCT ID: NCT04024592 Completed - Children Clinical Trials

Reliability and Validity of Strength Measurement of the Lower Limbs in Typically Developing Children

Start date: November 30, 2017
Phase: N/A
Study type: Interventional

Reliability of isokinetic strength measurement of the knee in typically developing children has yet been studied and seems to be good. Because in daily life activities strength of the hip- and ankle-joint muscles are also important, the investigators aim to study the reliability and validity of isokinetic strength measurements of the hip and ankle.

NCT ID: NCT04012567 Completed - Knee Clinical Trials

Safety and Effectiveness of BIOSURE RG in Cruciate Ligaments Reconstruction in Chinese

BIOSURE RG
Start date: December 17, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to compare the safety and effectiveness of Biosure Regenesorb Interference Screw versus BIOSURE HA Interference Screw (control device) in patients requiring reconstruction of cruciate ligaments of the knee. The trial results will be used for registration of Biosure Regenesorb Interference Screw in China. The primary efficacy endpoint of this study is Lysholm score at 12 months after operation. The non-inferiority testing is performed for efficiency of primary efficacy endpoint, and the test hypothesis is as follows: Invalid hypothesis: H0: μ1-μ2 ≤-δ Alternative hypothesis: H1: μ1-μ2 > -δ, where, μ1 and μ2 are the Lysholm scores in the investigational group and control group, respectively. δ is a non-inferiority critical value.

NCT ID: NCT03487172 Completed - Knee Clinical Trials

Sculptra Aesthetic for the Treatment of Upper Knee Skin Laxity

Start date: April 10, 2018
Phase: N/A
Study type: Interventional

All subjects will receive three, single-sided injections of PLLA, performed 1 month apart.