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Knee Pain Chronic clinical trials

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NCT ID: NCT06239649 Recruiting - Knee Osteoarthritis Clinical Trials

The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty

Start date: October 19, 2023
Phase:
Study type: Observational [Patient Registry]

In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria.

NCT ID: NCT06233630 Recruiting - Knee Osteoarthritis Clinical Trials

Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Total Knee Arthroplasty

Start date: March 30, 2024
Phase: Phase 4
Study type: Interventional

Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty

NCT ID: NCT06197958 Recruiting - Knee Pain Chronic Clinical Trials

Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome

Start date: October 20, 2023
Phase: N/A
Study type: Interventional

Patellofemoral pain syndrome is due to dysfunctional dynamic knee valgus resulting from decrease in strength of hip abductors or abnormal rear-foot eversion with pes pronatus valgus. It is also associated with vastus medialis/vastus lateralis disbalance, hamstring tightness or iliotibial tract tightness.

NCT ID: NCT06123715 Recruiting - Chronic Pain Clinical Trials

Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

PROVISION
Start date: April 16, 2024
Phase: Phase 2
Study type: Interventional

Phase II Multicentre, pilot, parallel-group, blinded, 1:1 randomized controlled trial to determine the feasibility of conducting a larger definitive trail of using vitamin C to reduce persistent pain in patients undergoing total knee arthroplasty surgery.

NCT ID: NCT06105788 Recruiting - Knee Osteoarthritis Clinical Trials

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).

NCT ID: NCT06094660 Recruiting - Clinical trials for Osteo Arthritis Knee

RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA

RADIOPHENOL
Start date: November 27, 2023
Phase: N/A
Study type: Interventional

A randomised controlled triall (RCT) with three parallel arms comparing the functional outcome of chemical ablation with phenol and radiofrequency ablation (RFA) of the genicular nerves with conservative treatment in patients with chronic knee pain caused by osteoarthritis (OA).

NCT ID: NCT06084403 Recruiting - Knee Osteoarthritis Clinical Trials

Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy. Selective blockade of the saphenous nerve in the adductor canal provides effective analgesia without quadriceps muscle weakness. It has been shown that the adductor canal block (ACB) block increases the spread of local anesthetics in a distal and proximal way. Therefore, the proximal spread of local anesthetics may cause possible quadriceps weakness. The distal spread of local anesthetics may increase analgesic effect via sciatic nerve. The different volumes for ACB is a topic of discussion. The aim of this study is to compare the different volumes of US-guided ACB performing for postoperative analgesia management after total knee arthroplasty surgery.

NCT ID: NCT06038240 Recruiting - Surgery Clinical Trials

Optimizing Pain Self-Management in Total Knee Arthroplasty

Start date: November 27, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy of a positive affect enhancing intervention designed to reduce pain and augment reward system function in knee osteoarthritis (KOA) patients undergoing total knee arthroplasty (TKA). The scientific premise is that patient use of a positive emotion generative practice - savoring meditation, which has been demonstrated to reduce pain in experimental laboratory settings, enhanced with a pain neuroscience education component about reward system dysfunction as a chronic pain mechanism - is optimally suited to reduce postsurgical pain and augment reward system functioning relative to a Pain Self-Management and Education (PSME) condition. We will randomize 150 patients with KOA undergoing unilateral TKA to a brief, 4-session (20-30 minutes each) course of Savoring Meditation (SM; n = 75) or PSME (n = 75) delivered remotely by trained interventionists in a one-on-one format. We will assess pain and as well as pain-related risk and protective factors both via questionnaire and via weeklong ecological momentary assessment (EMA) data bursts on the following schedule: baseline, post-surgery, and 3-month follow-up. In addition, participants will attend laboratory testing sessions at baseline and 6-weeks post-surgery, during which affective pain modulation and electroencephalographic (EEG) brain biomarkers associated with pain and affect will be recorded. Participants in SM be encouraged to practice their savoring for 5 minutes/day during the week following surgery, as well as to use it to manage pain flares in a self-directed manner.

NCT ID: NCT05971966 Recruiting - Clinical trials for Patellofemoral Pain Syndrome

Effects of Virtual Reality Rehabilitation and Muscle Energy Technique in Patients With Patellofemoral Pain Syndrome.

Start date: August 30, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to determine the effects of Virtual reality rehabilitation and muscle energy techniques in patients with patellofemoral pain syndrome for reducing pain, enhancing knee range of motion and improve functional activities.

NCT ID: NCT05965804 Recruiting - Knee Injuries Clinical Trials

Vastus Medialis Activation During McMurray's Test

Start date: July 25, 2023
Phase:
Study type: Observational

This study will use electromyography to evaluate activation patterns of the vastus medialis and vastus lateralis muscles during the McMurray's knee examination test in different knee positions.