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Knee Injuries clinical trials

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NCT ID: NCT04709133 Not yet recruiting - Knee Injuries Clinical Trials

Clinical Outcomes Of Multi-ligament Knee Injuries In Assiut University Hospitals

Start date: January 2021
Phase: N/A
Study type: Interventional

Multi-ligament knee injuries (MLKI) are devastating injuries. They are defined as injuries to at least two of the four major ligaments in the knee: anterior cruciate ligament, posterior cruciate ligament, lateral collateral ligament (and posterolateral corner) and medial collateral ligament (and posteromedial corner). These injuries are commonly classified using the Schenck classification system. The incidence of these injuries has been reported to be around 0.02-0.20% of all orthopaedic injuries. However, this is likely to be an underestimation due to spontaneous knee reduction and missed injuries. The immediate management of these injuries is crucial in identifying and treating any vascular and nerve injury. The literature has shown poor outcome and residual instability in those who were treated non-operatively. However, the optimal surgical treatment for these injuries is not known, with differences in opinion amongst treating clinicians. There are controversies in the timing of surgery (early versus delayed), single-staged or two-staged procedures and whether the damaged ligaments should be repaired or reconstructed

NCT ID: NCT04670042 Withdrawn - Surgery Clinical Trials

Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery

Start date: June 25, 2021
Phase: N/A
Study type: Interventional

SPRINT PNS System will be offered to patients with postoperative knee pain following primary unilateral total knee arthroplasty (TKA) who meet eligibility criteria and consistent with established coverage policy. SPRINT PNS System will be implanted for 60 days. At the discretion of the physician, the first lead may be placed to stimulate the nerve innervating the region of greatest pain. If pain is not adequately addressed by the first lead when assessed at 10 days, a second lead may be placed approximately 2 weeks following the initial lead placement.

NCT ID: NCT04653272 Completed - Knee Injuries Clinical Trials

Simple Knee Value, a Simple Score for Functional Assessment of the Knee

SKV
Start date: April 1, 2020
Phase:
Study type: Observational

The pre- and post-operative functional assessment of patients' knees is of great interest for the practitioner, whether it is in his or her daily practice to determine the appropriate management of the patient, or to conduct clinical studies. The scores used are established in several languages to provide a uniformly accepted unit of measurement.

NCT ID: NCT04554212 Recruiting - Wounds and Injuries Clinical Trials

Blood Flow Restriction Training After Patellar INStability

BRAINS
Start date: September 9, 2020
Phase: N/A
Study type: Interventional

This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.

NCT ID: NCT04550299 Recruiting - Knee Injuries Clinical Trials

ACL Reconstruction With Simple and Double Bundle Technique Using Two Different Implants for Graft Fixation

Start date: February 26, 2013
Phase: N/A
Study type: Interventional

In this study our objective is to compare two tibial ACL graft fixation systems in patients undergoing two different reconstructions technique (with simple and double bundle) in terms of tendon graft osteointegration, functionality and return to sports.

NCT ID: NCT04543227 Completed - Pain Clinical Trials

Opioid Laws and Pediatric Use

Start date: September 10, 2020
Phase:
Study type: Observational

The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an increased risk of opioid abuse and chronic use by patients. The overarching goal of application is to assess opioid use and outcomes of pediatric patients treated for either burn injuries or knee arthroscopy procedures at a large academic pediatric medical center before and after Ohio opioid prescription rules for acute pain were implemented on August 21, 2017. Also, to evaluate patient use of opioids at 90-days post-treatment.

NCT ID: NCT04537013 Recruiting - Knee Injuries Clinical Trials

Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee

SECURE
Start date: August 26, 2020
Phase: N/A
Study type: Interventional

Multi-center, prospective, concurrently controlled, non-randomized, double-blind (patient and assessor). Treatment of large chondral lesions in the knee with microfracture plus the Chondro-Gide® ACC is non-inferior to treatment of small chondral lesions treated with microfracture alone.

NCT ID: NCT04528992 Recruiting - Knee Injuries Clinical Trials

Effects of Blood Flow Restriction (BFR) Therapy on ACL Graft Maturation

Start date: May 2024
Phase: N/A
Study type: Interventional

This is a study comparing the effects of blood flow restriction (BFR) therapy on the maturation of the Anterior Cruciate Ligament (ACL) graft after reconstruction surgery compared to physical therapy without the use of BFR.

NCT ID: NCT04456530 Enrolling by invitation - Surgery Clinical Trials

Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study

Start date: May 8, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The loss of muscle mass post-surgery confounds recovery efforts and leads to a delay in patient's ability to return to activities. Although the use of testosterone in aging and chronic muscle loss has been investigated, this study could prove short-term use of testosterone efficacious in preventing muscle atrophy due to surgery. We hypothesize that by bracketing an indexed knee surgery with testosterone undecanoate injections, post-surgical quadriceps muscle loss may be minimized. Determination of the effect of intra-muscular (IM) testosterone injections in preventing quadriceps muscle loss are measured by serial MRI and manual measurements of quadriceps cross-section.

NCT ID: NCT04374968 Completed - Knee Injuries Clinical Trials

Use of Blood Flow Restriction Therapy Following ACL Tear

Start date: July 28, 2020
Phase: N/A
Study type: Interventional

Evaluating the use of peri-operative blood flow restriction therapy surrounding anterior cruciate ligament tear