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Knee Injuries clinical trials

View clinical trials related to Knee Injuries.

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NCT ID: NCT05420675 Completed - Clinical trials for Knee Injuries and Disorders

Different Arm Positions During Single Leg Squat

Start date: June 8, 2022
Phase:
Study type: Observational

The aim of this study is to compare the effects of different arm positions on muscle activity during single leg squat.

NCT ID: NCT05414942 Completed - Opioid Use Clinical Trials

Opioid Reduction Program for Total Knee Replacement Patients

TKR ORP
Start date: August 1, 2021
Phase: N/A
Study type: Interventional

In the context of prescribed opioids, research suggests that increased exposure is associated with long-term opioid use. Orthopedic surgeries are associated with the prescribing of more opioid narcotics than any other surgical specialty, particularly for Total Knee Replacement surgery, which is associated with severe post-operative pain. The proposed project is a randomized clinical trial to explore the efficacy of our Total Knee Replacement Opioid Reduction Program (ORP) vs. Treatment As Usual (TAU) in the reduction of opioid use following total knee replacement surgery.

NCT ID: NCT05364970 Recruiting - Knee Injuries Clinical Trials

IVR in Motor Rehabilitation

IVR_MOT
Start date: April 12, 2023
Phase: Early Phase 1
Study type: Interventional

The present project on sport rehabilitation aims at validating a rehabilitation protocol in immersive virtual reality (IVR) for restoring motor functions following peripheral injuries of the lower limbs. Sport injuries are related to direct and indirect costs and, in many cases, cause an interruption of motor activity for prolonged periods. Sport physiotherapy aims at recovering the motor functionality in order to guarantee the fastest possible return to sport. It employs plasticity and compensatory mechanisms within the injured motor system. However, being primarily based on the execution of movements that can be largely compromised, the treatment might be intrinsically complicated. It has been suggested that the motor system can be activated by observing one's own body perform the movements, without any actual movement execution. By using multisensory integration and sense of presence in IVR, it is possible to create an illusory experience that a moving virtual body (avatar) temporarily becomes one's own moving body. Moreover, this experience activates the motor system similarly to the activation from one's own actual movements. Based on these considerations, the present study hypothesizes that observation of one's own virtual body, without any movement execution, might activate the motor system to the extent of significantly improving functional recovery. The randomized clinical trial will recruit participants that underwent knee surgery and are in the first phase of the rehabilitation period (starting within two weeks after the surgery). Together with the traditional training protocol (4-6 weeks) participants will be administered a training in IVR that will include a virtual avatar performing a series of standard lower limb rehabilitation exercises. Participants will be randomly assigned to the experimental group (avatar observed from the first-person perspective, i.e., perceived as one's own body), the active control group (avatar observed from the third-person perspective, i.e., perceived as another person's body) and the group with no intervention. Before, at midpoint and after intervention, a standard battery of tests will be administered to evaluate the state of the motor system), as well as measures of embodiment for controlling the efficacy of the virtual scenario. The hypothesis is that the experimental group will show greater improvement of the motor functionality compared to the two control groups.

NCT ID: NCT05344001 Recruiting - Aging Clinical Trials

Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

Start date: April 18, 2022
Phase:
Study type: Observational

Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability. Quantifying function in former athletes with and without a prior injury and non-athlete controls is critical to understanding long-term health trajectories in athletes and informing potential interventional studies. One modifiable factor that may be associated with long-term health in athletes is physical activity patterns. The purpose of this study is to evaluate strength, function, physical activity, dietary patterns, and cardiometabolic health among current and former competitive athletes and in nonathlete controls to evaluate the impact of prior knee injury and sedentary behavior as two potential determinants of later poor health and reduced function.

NCT ID: NCT05335252 Recruiting - Knee Osteoarthritis Clinical Trials

Dronabinol After Arthroscopic Surgery

Start date: June 28, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pain, reduce opioid consumption and will result in few negative side effects. If this pilot study shows promising results the investigators will expand the trial to include additional arthroscopic surgeries (hip, shoulder) and other types of orthopaedic surgery.

NCT ID: NCT05328674 Recruiting - Knee Injuries Clinical Trials

Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defects in the Knee Joint With the Use of Autogenous Cartilage Graft With PRP GF (Platelet-rich Plasma With Growth Factors)

Start date: June 22, 2021
Phase: N/A
Study type: Interventional

Clinical and comparative evaluation of the treatment results of arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage graft with PRP GF (platelet-rich plasma with growth factors)

NCT ID: NCT05328544 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.

Start date: August 13, 2021
Phase: N/A
Study type: Interventional

Clinical and comparative evaluation of the results of autograft healing of the tendon of the semitendinus muscle in the tibial canal, after reconstruction of the anterior cruciate ligament of the knee joint, by the method of stabilization of the screw with a bioabsorbable method, with or without the use of autogenous spongiform bone grafts.

NCT ID: NCT05323474 Recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport

ORACL-Run
Start date: November 14, 2022
Phase: N/A
Study type: Interventional

Following reconstruction of the anterior cruciate ligament (ACL), a standardized rehabilitation protocol is carried out by a physiotherapist. In France, a well-established rehabilitation consensus guides the first phase of 3 months postoperatively and patient compliance is generally excellent. The next phase should allow a return to sport (RTS) following a continuum depending on the objectives of the sport's patient, starting with a return to running activities (RTR) and a preparatory phase for a RTS which may be authorized at 6 months post-op. This multicentre randomized control trial aims to evaluate the effectiveness of an individualized and optimized rehabilitation program guided by monthly assessments carried out by physiotherapists from the 3rd to the 6th month postoperatively to reduce the risk of new ACL injuries (operated or healthy knee), compared to standard management.

NCT ID: NCT05318118 Recruiting - Clinical trials for Medial Mensical Tear

Comparison of the Results of Arthroscopic Suturing of the Medial Meniscus Using the Fast Fix and FiberStitch Systems

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

Clinical and comparative evaluation of the treatment results of arthroscopic reconstruction of the medial meniscus of the knee joint using the Fast Fix and FiberStitch systems.

NCT ID: NCT05297175 Recruiting - Clinical trials for Knee Injuries and Disorders

AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation

AIR2
Start date: October 19, 2021
Phase: N/A
Study type: Interventional

The AIR2 Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® medial meniscus prosthesis.