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Knee Arthroplasty, Total clinical trials

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NCT ID: NCT03308071 Completed - Postoperative Pain Clinical Trials

Hypnosis for Symptom Management in Elective Orthopedic Surgery

Start date: September 20, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to determine if teaching self-hypnosis techniques to patients prior to knee replacement surgery will decrease their pain medication requirements, pain medication side-effects, length of stay in the hospital, readmission rates, pain, anxiety, physical function, satisfaction scores, and cost of admission.

NCT ID: NCT03276143 Completed - Clinical trials for Knee Arthroplasty, Total

FactOr XIa inhibiTion for the pRevention of venOus Thromboembolism in Patients Undergoing Total Knee Arthroplasty

FOXTROT
Start date: September 21, 2017
Phase: Phase 2
Study type: Interventional

This study was to compare the study drug BAY1213790 to existing therapies, i.e. enoxaparin or apixaban, for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA). The study was open-label, but observer-blinded for the different doses of BAY1213790. This means that it was known which treatment was given, but it was not known which dose of BAY1213790 was administered.

NCT ID: NCT02988947 Terminated - Clinical trials for Knee Arthroplasty, Total

Effectiveness of a Psychological Intervention in Patients Undergoing Total Knee Arthroplasty

PsInTKA
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a combined Pain Neuroscience Education (PNE) and Hypnosis (HyP) psychological intervention aiming at the control and prevention of pain and promotion of post-surgical recovery in patients undergoing Total Knee Arthroplasty

NCT ID: NCT02947321 Completed - Osteoarthritis Clinical Trials

Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial

Start date: January 26, 2018
Phase: N/A
Study type: Interventional

Given the benefits of genicular nerve radiofrequency ablation (RFA) in improving pain and functional status in non-surgical patients with knee osteoarthritis as well as the high prevalence of postoperative pain from total knee arthroplasty (TKA), this study is designed to determine the efficacy of preoperative genicular nerve RFA in improving acute and chronic postoperative pain as well as functional status in patients undergoing TKA. Patients will be randomized to one of two study arms: RFA group (genicular nerve thermal RFA) or control group (RFA needles placed in proper location without effective neurotomy).

NCT ID: NCT02830087 Terminated - Clinical trials for Knee Arthroplasty, Total

Tourniquet Pressure in Primary Total Knee Arthroplasty

Start date: June 2016
Phase: N/A
Study type: Interventional

This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and post-operative outcomes. This study does not seek to answer the question of "tourniquet vs no tourniquet", but to seek a tourniquet usage that would maximize the intraoperative benefits for the surgeon and minimize the negative consequences for patient outcomes. Specific Aim #1: enroll around 146 primary TKA patients. Specific Aim #2: evaluate different tourniquet cuff pressures (TCP) and tourniquet times in relation to intraoperative performance. Specific Aim #3: evaluate different TCP and tourniquet times in relation to post-operative pain and complications of short-term, intermediate, and long-term followup. Specific Aim #4: evaluate different TCP and tourniquet times in relation to post-operative function of short-term, intermediate, and long-term followup.

NCT ID: NCT02465827 Completed - Clinical trials for Knee Arthroplasty, Total

Ultrasound-guided Selective Blockade of the Saphenous and Obturator Nerves Following Total Knee Arthroplasty

Start date: January 2014
Phase: Phase 4
Study type: Interventional

The investigators aimed to evaluate the efficacy of selective low volume ultrasound-guided blockades of the saphenous and obturator nerves on dynamic and rest pain 24-hours post-operatively for patients undergoing unilateral primary total knee arthroplasty.

NCT ID: NCT02445443 Active, not recruiting - Clinical trials for Knee Arthroplasty, Total

LEGION Hinge Safety and Efficacy Study

LINKS
Start date: June 30, 2015
Phase:
Study type: Observational

The purpose of the current investigation is to assess the safety and efficacy of a new hinged revision knee device. This device is designed to provide efficient, reproducible reconstructions with optimal limb and implant alignment, durable implant fixation, and functional outcomes that increasingly approach those of primary Total Knee Arthroplasty (TKA).

NCT ID: NCT02429856 Completed - Clinical trials for Arthroplasty, Replacement, Knee

Posterior Cruciate Retaining (PCR) Versus Posterior Cruciate Substituting (PCS) Total Knee Arthroplasty (TKA)

SCORPIO™
Start date: February 1999
Phase: Phase 4
Study type: Interventional

This randomized clinical trial (RCT) examined 10 year outcomes comparing SCORPIO™ Posterior Cruciate Substituting (PCS) versus Posterior Cruciate Retaining (PCR) Total Knee Arthroplasty (TKA) as the primary outcome.

NCT ID: NCT02344589 Completed - Clinical trials for Knee Arthroplasty, Total

The Effect of Local Anesthetic Volume Within the Adductor Canal on Quadriceps Function Evaluated by Electromyography

Start date: January 2015
Phase: Phase 4
Study type: Interventional

Our aim is to investigate which components of the quadriceps femoris muscle are affected following an ACB with different volumes (10, 20 and 30 ml) of 1% lignocaine evaluated by electromyography. Both a placebo treatment (20ml saline) and the femoral nerve block (20ml lignocaine 1%) as an active comparative will be used for model control. Further, we want to investigate the effect of volume on motor block. This will be evaluated by measuring the Maximum Voluntary Isometric Contraction (MVIC) of the quadriceps femoris muscle.

NCT ID: NCT02327117 Recruiting - Clinical trials for Knee Arthroplasty, Total

Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial

Start date: January 2013
Phase: N/A
Study type: Interventional

Total Knee Arthroplasty (TKA) is a common orthopedic surgery usually leads to Bleeding. The null hypothesis of this study was that TA has no effect on post surgical bleeding in patients undergoes TKA.