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Kidney Tumor clinical trials

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NCT ID: NCT06056505 Recruiting - Kidney Tumor Clinical Trials

Virtual Interactive 3D Modelling to Improve Outcomes in Robotic-Assisted Partial Nephrectomy

3DPN
Start date: October 24, 2023
Phase: N/A
Study type: Interventional

The primary objective is to determine if 3D modelling shortens total console operation time as a surrogate endpoint for clinical outcomes like perioperative complications and morbidity in robotic-assisted partial nephrectomy.

NCT ID: NCT05890781 Recruiting - Sarcoma Clinical Trials

Engineering Immune Organoids to Study Pediatric Cancer

IMMUNEORGANOID
Start date: May 12, 2023
Phase: N/A
Study type: Interventional

To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)

NCT ID: NCT05728957 Recruiting - Kidney Tumor Clinical Trials

Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors

BIOPSy
Start date: February 1, 2023
Phase:
Study type: Observational

The goal of this clinical trial is to better tell apart whether kidney tumors are benign (not cancer) or malignant (cancer) based on a biopsy or imaging tests and ask patients how they feel about decisions they make about treatment of their kidney tumor. The main objectives are: To estimate and compare the diagnostic accuracy of renal mass biopsy alone, PEER (with renal mass biopsy), and 99mTc-sestamibi SPECT/CT (with renal mass biopsy for hot tumors) to differentiate malignant and benign renal tumors. To estimate and compare the diagnostic accuracy of renal mass biopsy, PEER (with renal mass biopsy), and 99mTc-sestamibi SPECT/CT (with renal mass biopsy for hot tumors) to differentiate oncocytoma from chromophobe RCC. Participants will be asked to complete survey questions related to their health and kidney tumor at the start and end of the study. These can be done on paper, electronically, or by telephone.

NCT ID: NCT05387863 Recruiting - Renal Cancer Clinical Trials

Decision Aid (DA) for Renal Patients

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to understand how patients make decisions about treating their kidney masses, and to identify key values and preferences for treating their kidney masses. The study team will develop a decision aid (DA) using the decision-analytic model to communicate personalized benefit/harm estimates to patients and promote patient-centered treatment of renal tumors.

NCT ID: NCT05015179 Completed - Kidney Tumor Clinical Trials

Mixed Reality Technology in Laparoscopic Partial Nephrectomy

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The aim of our study was: a) to evaluate the usefulness of the MR model for renal pedicle exposure and identification of the tumor's exact location during LPN, and b) to evaluate the subjective utility of the MR model as an intraoperative reference tool. Investigators prospectively enrolled 47 patients with LPN between June 2020 and February 2021. Patients were randomly assigned into two groups: the control group (24 patients), who underwent operation with an intraoperative ultrasound (US) control and the experimental group (23 patients), who underwent operation with the aid of the MR model. Randomization was performed using a computerized randomization program and sealed envelopes. Patients were included in the study if they were 18 years of age or older, were able to sign informed consent, and had T1a renal tumors amenable to LPN. Patients were excluded if they were unwilling to participate or did not meet the inclusion criteria. For each patient, investigators prospectively collected demographic data including age, body mass index, clinical tumor size, side, location, and complexity score according to the PADUA scoring system; perioperative data (including time for renal pedicle exposure and time for renal tumor detection and duration of ischemia); pathological data; data on postoperative functional outcome and complications, classified according to the Clavien-Dindo system.

NCT ID: NCT03819569 Active, not recruiting - Kidney Tumor Clinical Trials

GRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses

GRADE-SRM
Start date: October 30, 2018
Phase: N/A
Study type: Interventional

Purpose: The purpose of this study is to evaluate the role of renal mass biopsy on decision-making for patients presenting with clinical T1 kidney tumors. This study also incorporates integrated biomarker study to compare the genomic data obtained through biopsy tissue to genomic information from surgical data.

NCT ID: NCT01967407 Recruiting - Renal Cell Cancer Clinical Trials

IReversible Electroporation of Kidney Tumors Before Partial Nephrectomy.

IRENE
Start date: October 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the study is the evaluation of the ablation efficiency of the percutaneous irreversible electroporation (IRE) as primary ablation therapy of locally confined renal cell carcinoma (≤4cm, see inclusion and exclusion criteria). The ablation success will be proofed by magnet resonance imaging (MRI) and histologically after partial kidney resection or nephrectomy 4 weeks after IRE. Hypotheses: Kidney tumors ≤4cm can be ablated completely by percutaneous IRE. Surrounded structures and renal tissue can be preserved.

NCT ID: NCT01950923 Completed - Kidney Tumor Clinical Trials

Sildenafil Citrate Before Surgery in Improving Kidney Function in Patients With Kidney Cancer

Start date: September 2013
Phase: Phase 1
Study type: Interventional

This randomized pilot clinical trial studies sildenafil citrate before surgery in improving kidney function in patients with kidney cancer. Sildenafil citrate may help protect the kidney from the side effects of surgery and improve kidney function after surgery.

NCT ID: NCT01908166 Completed - Kidney Tumor Clinical Trials

Ultrasound Elastography in Diagnosing Patients With Kidney or Liver Solid Focal Lesions

Start date: January 2014
Phase: N/A
Study type: Interventional

This clinical trial studies ultrasound elastography in diagnosing patients with kidney or liver solid focal lesions. New diagnostic procedures, such as ultrasound elastography, may be a less invasive way to check for kidney or liver solid focal lesions.

NCT ID: NCT01688414 Withdrawn - Prostate Cancer Clinical Trials

Imaging During Surgery in Diagnosing Patients With Prostate, Bladder, or Kidney Cancer

Start date: September 2012
Phase: N/A
Study type: Interventional

This pilot clinical trial studies imaging during surgery in diagnosing patients with prostate, bladder, or kidney cancer. New diagnostic imaging procedures, may find prostate, bladder, or kidney cancer