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Kidney Tumor clinical trials

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NCT ID: NCT05015179 Completed - Kidney Tumor Clinical Trials

Mixed Reality Technology in Laparoscopic Partial Nephrectomy

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The aim of our study was: a) to evaluate the usefulness of the MR model for renal pedicle exposure and identification of the tumor's exact location during LPN, and b) to evaluate the subjective utility of the MR model as an intraoperative reference tool. Investigators prospectively enrolled 47 patients with LPN between June 2020 and February 2021. Patients were randomly assigned into two groups: the control group (24 patients), who underwent operation with an intraoperative ultrasound (US) control and the experimental group (23 patients), who underwent operation with the aid of the MR model. Randomization was performed using a computerized randomization program and sealed envelopes. Patients were included in the study if they were 18 years of age or older, were able to sign informed consent, and had T1a renal tumors amenable to LPN. Patients were excluded if they were unwilling to participate or did not meet the inclusion criteria. For each patient, investigators prospectively collected demographic data including age, body mass index, clinical tumor size, side, location, and complexity score according to the PADUA scoring system; perioperative data (including time for renal pedicle exposure and time for renal tumor detection and duration of ischemia); pathological data; data on postoperative functional outcome and complications, classified according to the Clavien-Dindo system.

NCT ID: NCT01950923 Completed - Kidney Tumor Clinical Trials

Sildenafil Citrate Before Surgery in Improving Kidney Function in Patients With Kidney Cancer

Start date: September 2013
Phase: Phase 1
Study type: Interventional

This randomized pilot clinical trial studies sildenafil citrate before surgery in improving kidney function in patients with kidney cancer. Sildenafil citrate may help protect the kidney from the side effects of surgery and improve kidney function after surgery.

NCT ID: NCT01908166 Completed - Kidney Tumor Clinical Trials

Ultrasound Elastography in Diagnosing Patients With Kidney or Liver Solid Focal Lesions

Start date: January 2014
Phase: N/A
Study type: Interventional

This clinical trial studies ultrasound elastography in diagnosing patients with kidney or liver solid focal lesions. New diagnostic procedures, such as ultrasound elastography, may be a less invasive way to check for kidney or liver solid focal lesions.

NCT ID: NCT00019630 Completed - Brain Tumor Clinical Trials

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

Start date: July 1999
Phase: Phase 1
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of liposomal doxorubicin in treating children who have refractory solid tumors.