Immunosuppression Reduction in Failed Allograft Guided by cfDNA

Status Withdrawn

Clinical Trial Summary

The optimal timing for immunosuppression tapering for patients with failed kidney transplant is not known. This pilot study would be to correlate rise in cf-DNA and increase in cPRA.

Clinical Trial Description

This is an observational cohort study collecting data and blood specimens at designated time points. The primary outcome will be comparing the cPRA in patients that have a rise in cf-DNA to those that do not have a rise in cf-DNA. Seondary outcomes include comparison of the combined incidence of need for transfusion, need for methylprednisolone and allograft nephrectomy, ESA dose, allograft tenderness, and gross hematuria. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04560582
Study type	Observational
Source	University of Minnesota
Contact
Status	Withdrawn
Phase
Start date	September 22, 2022
Completion date	October 2023

View Details

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